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Graves N, Wloch C, Wilson J, et al. A cost-effectiveness modelling study of strategies to reduce risk of infection following primary hip replacement based on a systematic review. Southampton (UK): NIHR Journals Library; 2016 Jul. (Health Technology Assessment, No. 20.54.)

Cover of A cost-effectiveness modelling study of strategies to reduce risk of infection following primary hip replacement based on a systematic review

A cost-effectiveness modelling study of strategies to reduce risk of infection following primary hip replacement based on a systematic review.

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Appendix 1Search terms and strategies used for updating existing evidence

MEDLINE search strategy and output

Date of search: August 2011.

Date range searched: January 1966 to June 2011.

Search strategy

  1. MH “arthroplasty, replacement, hip’ (12,088)
  2. MH”Hip prosthesis” (16,064)
  3. or/1-2 (23,923)
  4. MH “Surgical wound infection” (24,907)
  5. MH “prosthesis-related infections” (5875)
  6. MH “sepsis+” (78,337)
  7. MH “bacterial infections+” (651,285)
  8. or/4-7 (718,898)
  9. MH “infection control+’ (44,638)
  10. infection prevent*/ (33,276)
  11. MH “antibiotic prophylaxis” (6889)
  12. MH “anti-infective agents+” (427,375)
  13. MH “Anti-Bacterial Agents+” (226,839)
  14. intravenous antibiotics/ (3008)
  15. systemic antibiotics/ (2001)
  16. or/9-15 (489,991)
  17. MH “bone cements” (7563)
  18. Antibiotic cement/ (448)
  19. antibiotic bone cement (smart text searching)/ (7715)
  20. Antibiotic-impregnated cement (smart text searching)/ (733)
  21. Antibiotic-impregnated bone cement (smart text searching )/ (1001)
  22. Antibiotic-loaded cement (smart text searching)/ (1129)
  23. Antibiotic-loaded bone cement (smart text s)/ (7969)
  24. MH “Environment, Controlled+” (218,646)
  25. MH “ventilation” (4202)
  26. MH “Air conditioning” (2075)
  27. MH “operating rooms” (9370)
  28. Operating theatre/ (1937)
  29. laminar air flow (smart text searching)/ (3374)
  30. laminar airflow (smart text searching )/ (244)
  31. laminar air flow system (smart text searching) (4345)
  32. ultra-clean air (smart text searching )/ (2527)
  33. ultra clean air (smart text searching)/ (2527)
  34. ultra-clean air system (smart text searching) (4496)
  35. conventional operating room (smart text searching)/ (22,235)
  36. conventional operating theatre (smart text searching)/ (2777)
  37. Turbulent air flow (smart text searching)/ (2613)
  38. or/25-38 (256,457)
  39. 3 and 8 and 16 (697)
  40. 3 and 8 and 24 (292)
  41. 3 and 8 and 39 (87)
  42. 40 or 41 or 42 (834)
  43. Limit 43 to 2004-2011 (01/01/2004-01/06/2011) (343)
  44. Limit 44 to English (289)

Cumulative Index to Nursing and Allied Health Literature search strategy and output

Date of search: August 2011.

Date range searched: January 1966 to June 2011.

Search strategy

  1. MH “arthroplasty, replacement, hip’ (4105)
  2. MH “joint prosthesis” (2008)
  3. Hip prosthesis (smart text searching) (1894)
  4. or/1-3 (5474)
  5. MH “Surgical wound infection” (3410)
  6. MH “prosthesis-related infections” (529)
  7. MH “sepsis+” (7640)
  8. MH “bacterial infections+” (39,831)
  9. or/5-8 (48,616)
  10. MH “infection control+’ (31,116)
  11. infection prevent*/ (10,134)
  12. MH “antibiotic prophylaxis” (2227)
  13. MH “anti-infective agents+” (45,136)
  14. Anti-Bacterial Agents (smart text searching)/ (2578)
  15. intravenous antibiotics (smart text searching)/ (1301)
  16. systemic antibiotics (smart text searching)/ (665)
  17. or/10-16 (79,414)
  18. MH “bone cements” (804)
  19. Antibiotic cement (smart text searching) (96)
  20. antibiotic bone cement (smart text searching)/ (610)
  21. Antibiotic-impregnated cement (smart text searching)/ (107)
  22. Antibiotic-impregnated bone cement (smart text searching )/ (126)
  23. Antibiotic-loaded cement (smart text searching)/ (144)
  24. Antibiotic-loaded bone cement (smart text s)/ (638)
  25. MH “Environment, Controlled+” (4265)
  26. MH “ventilation+” (747)
  27. MH “Air conditioning” (118)
  28. MH “operating rooms” (4319)
  29. Operating theatre (smart text searching) (663)
  30. laminar air flow (smart text searching) (126)
  31. laminar airflow (smart text searching )/ (38)
  32. laminar air flow system (smart text searching) (137)
  33. ultra-clean air (smart text searching )/ (40)
  34. ultra clean air (smart text searching)/ (40)
  35. ultra-clean air system (smart text searching) (126)
  36. conventional operating room (smart text searching)/ (359)
  37. conventional operating theatre (smart text searching)/ (664)
  38. Turbulent air flow (smart text searching)/ (52)
  39. or/26-39 (9280)
  40. 4 and 9 and 17 (216)
  41. 4 and 9 and 25 (59)
  42. 4 and 9 and 40 (24)
  43. 41 or 42 or 43 (233)
  44. Limit 44 to 2004-2011 (01/01/2004-01/06/2011) (196)
  45. Limit 45 to English (196)

The Cochrane Central Register of Controlled Trials search strategy and search output

Date of search: August 2011.

Date range searched: January 1966 to June 2011.

Search strategy

#1. MH “arthroplasty, replacement, hip +”/exp (1254)

#2. MH”Hip prosthesis”/exp (942)

#3. or/1-2 (1949)

#4. MH “Surgical wound infection”/exp (2470)

#5. MH “prosthesis-related infections”/exp (127)

#6. MH “sepsis ”/exp (2684)

#7. MH “bacterial infections”/exp (13,168)

#8. or/4-7 (17,095)

#9. MH “infection control”/exp (1116)

#10. infection prevent*/ (16,554)

#11. MH “antibiotic prophylaxis”/exp (1040)

#12. MH “anti-infective agents”/exp (44,153)

#13. MH “Anti-Bacterial Agents”/exp (18,759)

#14. intravenous antibiotics/ (2375)

#15. systemic antibiotics/ (1220)

#16. or/9-15 / (55,871)

#17. MH “bone cements”/ exp (579)

#18. Antibiotic cement/ (39)

#19. antibiotic bone cement/ (32)

#20. Antibiotic-impregnated cement/ (7)

#21. Antibiotic-impregnated bone cement/ (7)

#22. Antibiotic-loaded cement/ (3)

#23. Antibiotic-loaded bone cement/ (3)

#24. or/17-23 (601)

25. MH “Environment, Controlled”/exp (1948)

26. MH “ventilation”/exp (52)

27. MH “Air conditioning”/exp (25)

28. MH “operating rooms”/exp (230)

29. Operating theatre/ (402)

30. laminar air flow/ (39)

31. laminar airflow/ (11)

32. laminar air flow system/ (7)

33. ultra-clean air/ (5)

34. ultra clean air/ (6)

35. ultra-clean air system/ (2)

36. conventional operating room/ (184)

37. conventional operating theatre/ (59)

38. Turbulent air flow/ (5)

39. or/25-38 (2697)

40. 3 and 8 and 16/ (58)

41. 3 and 8 and 24/ (9)

42. 3 and 8 and 39/ (11)

43. 40 or 41 or 42/ (59)

44. Limit 43 to 2004-2011 (15)

45. Limit 44 to English (15)

EMBASE search strategy and search output

Date of search: August 2011.

Date range searched: January 1966 to June 2011.

Search strategy

#1. ‘hip arthroplasty’/exp (32,814)

#2. ‘hip prosthesis’/exp (26,568)

#3. #1 OR #2 (32,814)

#4. ‘surgical infection’/exp (18,425)

#5. ‘prosthesis infection’/exp (2624)

#6. ‘sepsis’/exp (129,060)

#7. ‘bacterial infection’/exp (667,479)

#8. #4 OR #5 OR #6 OR #7 (767,273)

#9. ‘infection control’/exp (55,345)

#10. ‘infection prevention’/exp (31,360)

#11. ‘antibiotic prophylaxis’/exp (16,495)

#12. ‘antiinfective agent’/exp (1,827,014)

#13. ‘antibiotic agent’/exp (833,849)

#14. ‘intravenous’/exp AND ‘antibiotics’/exp (57,368)

#15. systemic AND ‘antibiotics’/exp (70,947)

#16. #9 OR #10 OR #11 OR #12 OR #13 OR #14 OR #15 (1,886,128)

#17. ‘bone cement’/exp (9336)

#18. ‘antibiotic’/exp AND ‘cement’/exp (1532)

#19. ‘antibiotic’/exp AND ‘bone’/exp AND ‘cement’/exp (340)

#20. ‘antibiotic’/exp AND impregnated (1038)

#21. ‘gentamicin bone cement’/exp (343)

#22. ‘antibiotic loaded’ AND ‘cement’/exp (204)

#23. ‘antibiotic loaded’ AND ‘bone’/exp AND ‘cement’/exp (31)

#24. #17 OR #18 OR #19 OR #20 OR #21 OR #22 OR #23 (10,339)

#25. ‘microclimate’/exp (30,703)

#26. ‘air conditioning’/exp (10,256)

#27. ‘operating room’/exp (15,854)

#28. ‘laminar airflow’/exp (566)

#29. laminar AND ‘air’/exp AND ‘flow’/exp AND system (29)

#30. ‘ultra clean’ AND ‘air’/exp (15)

#31. ultra AND clean AND ‘air’/exp (16)

#32. ‘ultra clean’ AND ‘air’/exp AND system (2)

#33. conventional AND operating AND room (886)

#34. conventional AND operating AND theatre (135)

#35. ‘turbulent flow’/exp (2813)

#36. #25 OR #26 OR #27 OR #28 OR #29 OR #30 OR #31 OR #32 OR #33 OR #34 OR #35 (49,434)

#37. #3 AND #8 AND #16 (828)

#38. #3 AND #8 AND #24 (226)

#39. #3 AND #8 AND #36 (37)

#40. #37 OR #38 OR #39 (915)

#41. #37 OR #38 OR #39 AND [english]/lim AND [2004-2011]/py (529)

#42. #37 OR #38 OR #39 AND [english]/lim AND [embase]/lim NOT [medline]/lim AND [2004-2011]/py (140)

Copyright © Queen’s Printer and Controller of HMSO 2016. This work was produced by Graves et al. under the terms of a commissioning contract issued by the Secretary of State for Health. This issue may be freely reproduced for the purposes of private research and study and extracts (or indeed, the full report) may be included in professional journals provided that suitable acknowledgement is made and the reproduction is not associated with any form of advertising. Applications for commercial reproduction should be addressed to: NIHR Journals Library, National Institute for Health Research, Evaluation, Trials and Studies Coordinating Centre, Alpha House, University of Southampton Science Park, Southampton SO16 7NS, UK.

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Bookshelf ID: NBK374328
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