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National Guideline Centre (UK). Preoperative Tests (Update): Routine Preoperative Tests for Elective Surgery. London: National Institute for Health and Care Excellence (NICE); 2016 Apr. (NICE Guideline, No. 45.)
16.1. Introduction
Urinalysis is the physical, chemical and microscopic analysis of urine. In the preoperative setting, it may be used to detect urinary tract infections, renal diseases and poorly controlled diabetes. The test is safe with no known risks. However, it is uncertain whether the test provides valuable information in asymptomatic individuals, and other more specific tests may be used to diagnose and monitor diabetes and renal disease. In addition, the clinical effectiveness of routine preoperative urinalysis is uncertain.
See section 4.4 for a summary of the methodological approach taken for this preoperative test.
16.2. Delphi survey results
As no new evidence on the use of urine dipstick tests as a routine preoperative test was identified during the scoping phase of this guideline it was decided not to carry out an evidence review, but to include urinalysis in the modified Delphi survey to re-evaluate the consensus held amongst health professionals on the value of routinely conducting the test prior to elective surgery.
The survey participants were asked if urine tests (urine dipstick) should be used as a routine preoperative test for patients undergoing elective surgery. Participants rated their response from strongly disagree to strongly agree using a nine-point Likert scale. Each question was considered to have reached consensus if greater than 70% of responses were in a single category (0–3 strongly disagree, 4–6 unclear, 7–9 strongly agree). Please see Appendix L for full details on the survey method and results.
16.2.1. Delphi statements where consensus was reached
Table 138Patients: ASA1
Surgery grade | Results % (round in which consensus was achieved) |
---|---|
Minor surgery | 86.45 strongly disagree (round 1) |
Intermediate surgery | 77.41 strongly disagree (round 1) |
Table 139Patients: ASA2 with cardiovascular, respiratory, renal or obesity comorbidities
Surgery grade | Results % (round in which consensus was achieved) |
---|---|
Minor surgery | 75.32 strongly disagree (round 1) |
Table 140Patients: ASA3 or ASA4 with cardiovascular, respiratory, renal or obesity comorbidities
Surgery grade | Results % (round in which consensus was achieved) |
---|---|
Minor surgery | 70.20 strongly disagree (round 1) |
16.2.2. Delphi statements where consensus was not reached
Table 141Patients: ASA1
Surgery grade | Results % | ||
---|---|---|---|
Round of Delphi | Strongly disagree | Strongly agree | |
Major or complex | 1 | 66.87 | 26.11 |
2 | 59.26 | 28.4 | |
3 | 63.76 | 23.2 |
Table 142Patients: ASA2 with diabetes
Surgery grade | Results % | ||
---|---|---|---|
Round of Delphi | Strongly disagree | Strongly agree | |
Minor surgery | 1 | 69.62 | 22.78 |
Intermediate surgery | 63.05 | 29.75 | |
Major or complex surgery | 61.54 | 34.62 | |
Minor surgery | 2 | 54.43 | 21.52 |
Intermediate surgery | 45.57 | 35.44 | |
Major or complex surgery | 42.86 | 30.01 | |
Minor surgery | 3 | 55.88 | 25.0 |
Intermediate surgery | 44.12 | 38.24 | |
Major or complex surgery | 32.84 | 50.75 |
Table 143Patients: ASA2 with cardiovascular, respiratory, renal or obesity comorbidities
Surgery grade | Results % | ||
---|---|---|---|
Round of Delphi | Strongly disagree | Strongly agree | |
Intermediate surgery | 1 | 68.35 | 23.42 |
Major or complex surgery | 63.69 | 33.75 | |
Intermediate surgery | 2 | 50.63 | 24.04 |
Major or complex surgery | 39.44 | 28.17 | |
Intermediate surgery | 3 | 52.18 | 23.19 |
Major or complex surgery | 40.58 | 42.03 |
Table 144Patients: ASA3 or ASA4 with diabetes
Surgery grade | Results % | ||
---|---|---|---|
Round of Delphi | Strongly disagree | Strongly agree | |
Minor surgery | 1 | 64.56 | 27.22 |
Intermediate surgery | 61.15 | 31.85 | |
Major or complex surgery | 60.65 | 34.19 | |
Minor surgery | 2 | 43.75 | 33.75 |
Intermediate surgery | 37.5 | 43.75 | |
Major or complex surgery | 32.4 | 42.25 | |
Minor surgery | 3 | 43.29 | 32.84 |
Intermediate surgery | 36.23 | 43.47 | |
Major or complex surgery | 31.34 | 58.21 |
Table 145Patients: ASA3 or ASA4 with cardiovascular, respiratory, renal or obesity comorbidities
Surgery grade | Results % | ||
---|---|---|---|
Round of Delphi | Strongly disagree | Strongly agree | |
Intermediate surgery | 1 | 65.19 | 27.21 |
Major or complex surgery | 62.42 | 35.03 | |
Intermediate surgery | 2 | 41.78 | 36.7 |
Major or complex surgery | 35.75 | 41.43 | |
Intermediate surgery | 3 | 42.03 | 30.44 |
Major or complex surgery | 36.23 | 42.03 |
16.3. Economic evidence
Unit costs were provided for consideration alongside the Delphi survey results. Please see Appendix M for details. These are reported in Table 146 and Table 147 below.
16.4. Recommendations and link to evidence
Recommendations |
|
---|---|
Delphi | The GDG discussed the results of the Delphi survey and felt they were more conservative than the consensus of the GDG. While consensus was not reached to ‘offer’ the test to any group, the majority opinion from the Delphi survey was to consider the test. The GDG believed that this was probably due to historical use of urine dipstick tests to pick up UTIs. However the GDG noted that urine dipstick tests are not sensitive or specific in the diagnosis of UTIs. A midstream urine sample (MSU) is considered to be the definitive diagnostic test for UTI. If a UTI would influence surgical decision-making, then the GDG suggests performing an MSU within an appropriate timeframe for the surgery. The GDG also discussed the value of the urine dipstick test as a quick and cheap screen for diabetes, however in keeping with other guidance, agreed that urine dipsticks should not be used routinely for screening or diagnosis of diabetes mellitus. |
Economic considerations | The cost of performing a urine dipstick test was found to be £3.85, including staff time and equipment. The cost is based on a dipstick test measuring 10 parameters (urine protein, glucose, nitrite, haemoglobin, ketones, bilirubin, urobilinogen, leukocytes, pH and specific gravity). The cost of using a urinalysis analyser was found to be £4.07. The GDG considered the cost of potential further investigations that could arise due to an abnormal result including ultrasounds (cost at £59) or a urology outpatient visit (cost at £99). Based on the results of the Delphi and GDG opinion, it is unlikely to be cost-effective to carry out a urine test in the majority of patients prior to elective surgery. The GDG felt that urine dipstick tests had poor diagnostic accuracy for identifying complications, and in the majority of cases identifying complications would not lead to a change in management that would improve health outcomes. The GDG recognised that urine testing potentially holds screening benefits, such as diagnosing early diabetes. However, this is not a gold standard diagnostic tool and there are already screening pathways in place to pick up such diseases. The GDG noted however that identifying a urinary tract infection (UTI) could have an impact on some individuals undergoing certain types of surgery, so narrowing down testing to this subset of patients could be a cost-effective use of NHS resources. |
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