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Excerpt
The objective of the systematic review is to compare the clinical and cost-effectiveness of oral antithrombotic agents (i.e., anticoagulant and antiplatelet agents) for the prevention of stroke and other thromboembolic events in patients with atrial fibrillation.
Contents
This report is prepared by the Canadian Agency for Drugs and Technologies in Health (CADTH). This report was guided by expert input and advice throughout its preparation. The information in this report is intended to help health care decision-makers, patients, health care professionals, health systems leaders, and policy-makers make well-informed decisions and thereby improve the quality of health care services. The information in this report should not be used as a substitute for the application of clinical judgment in respect to the care of a particular patient or other professional judgment in any decision-making process, nor is it intended to replace professional medical advice. While CADTH has taken care in the preparation of this report to ensure that its contents are accurate, complete, and up-to-date, CADTH does not make any guarantee to that effect. CADTH is not responsible for any errors or omissions or injury, loss, or damage arising from or as a result of the use (or misuse) of any information contained in or implied by the information in this report.
CADTH takes sole responsibility for the final form and content of this report. The statements, conclusions, and views expressed herein do not necessarily represent the view of Health Canada or any provincial or territorial government.
Production of this report is made possible through a financial contribution from Health Canada and the governments of Alberta, British Columbia, Manitoba, New Brunswick, Newfoundland and Labrador, Northwest Territories, Nova Scotia, Nunavut, Ontario, Prince Edward Island, Saskatchewan, and Yukon.
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- Review Antithrombotic and Anticoagulant Therapy for Atrial Fibrillation.[Heart Fail Clin. 2016]Review Antithrombotic and Anticoagulant Therapy for Atrial Fibrillation.Dzeshka MS, Lip GY. Heart Fail Clin. 2016 Apr; 12(2):257-71.
- Cost-effectiveness of apixaban versus other new oral anticoagulants for stroke prevention in atrial fibrillation.[Clin Ther. 2014]Cost-effectiveness of apixaban versus other new oral anticoagulants for stroke prevention in atrial fibrillation.Lip GY, Kongnakorn T, Phatak H, Kuznik A, Lanitis T, Liu LZ, Iloeje U, Hernandez L, Dorian P. Clin Ther. 2014 Feb 1; 36(2):192-210.e20. Epub 2014 Feb 6.
- Antiplatelet therapy for stable coronary artery disease in atrial fibrillation patients taking an oral anticoagulant: a nationwide cohort study.[Circulation. 2014]Antiplatelet therapy for stable coronary artery disease in atrial fibrillation patients taking an oral anticoagulant: a nationwide cohort study.Lamberts M, Gislason GH, Lip GY, Lassen JF, Olesen JB, Mikkelsen AP, Sørensen R, Køber L, Torp-Pedersen C, Hansen ML. Circulation. 2014 Apr 15; 129(15):1577-85. Epub 2014 Jan 27.
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