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Omega-3 Fatty Acids for Proteinuria due to Nephrotic Syndrome: A Review of Clinical Effectiveness and Cost-Effectiveness [Internet]. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2016 Feb 5.

Cover of Omega-3 Fatty Acids for Proteinuria due to Nephrotic Syndrome: A Review of Clinical Effectiveness and Cost-Effectiveness

Omega-3 Fatty Acids for Proteinuria due to Nephrotic Syndrome: A Review of Clinical Effectiveness and Cost-Effectiveness [Internet].

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KEY FINDINGS

Four systematic reviews and two non-randomized studies were identified regarding the clinical effectiveness of omega-3 fatty acid supplementation for reduction of proteinuria in patients with immunoglobulin A nephropathy or idiopathic steroid-resistant nephrotic syndrome. There is insufficient evidence to suggest a benefit of omega-3 treatment for these indications. There is some limited low quality evidence to suggest potential improvements in surrogate kidney function outcomes, but not relevant clinical endpoints, and no evidence of potential harm. No relevant evidence was identified regarding the cost-effectiveness of omega-3 fatty acids for patients with nephrotic syndrome.

Copyright © 2016 Canadian Agency for Drugs and Technologies in Health.

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Except where otherwise noted, this work is distributed under the terms of a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International licence (CC BY-NC-ND), a copy of which is available at http://creativecommons.org/licenses/by-nc-nd/4.0/

Bookshelf ID: NBK350634

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