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Structured Abstract
Background:
Impaired visual acuity is common in older adults. In 2009, the U.S. Preventive Services Task Force (USPSTF) found insufficient evidence to assess the balance of benefits and harms of screening for visual acuity in older adults (I statement).
Purpose:
This review updates the prior USPSTF review and will be used by the USPSTF to update its 2009 recommendation. It focuses on screening for impaired visual acuity and treatment of the following conditions: uncorrected refractive errors, cataracts, and age-related macular degeneration (AMD).
Data Sources:
We searched the Cochrane Central Register of Controlled Trials, the Cochrane Database of Systematic Reviews, and MEDLINE (2008 to January 2016) and manually reviewed reference lists.
Study Selection:
At least two reviewers independently evaluated each study to determine inclusion eligibility. We selected studies on screening versus no screening, delayed screening, or usual care; the diagnostic accuracy of screening tests in primary care settings; and treatment versus sham therapy, placebo, or no treatment for uncorrected refractive errors, cataracts, and AMD.
Data Extraction:
We abstracted details about the study design, patient population, setting, screening method, interventions, analysis, followup, and results. Two investigators independently applied criteria developed by the USPSTF to rate the quality of each study as good, fair, or poor using a consensus process.
Data Synthesis (Results):
Three cluster-randomized trials (all previously included in the 2009 USPSTF review) found no difference between vision screening versus no vision screening, usual care, or delayed screening on vision and other clinical outcomes. New evidence on the effectiveness of treatments versus placebo, sham, or no treatment was limited and did not change prior conclusions that effective treatments are available for uncorrected refractive error, cataracts, and AMD. New evidence on the diagnostic accuracy of screening tests for impaired visual acuity was also limited and did not change conclusions that screening questions or a questionnaire are inaccurate compared to a visual acuity test (e.g., the Snellen eye chart) or that a visual acuity test has suboptimal accuracy compared to a comprehensive ophthalmological examination; however, the clinical relevance of visual conditions identified on a comprehensive ophthalmological examination but not associated with impaired visual acuity is uncertain.
Limitations:
We included previously published systematic reviews, only included English-language studies, and could not assess for publication bias due to small numbers of studies.
Conclusions:
Impaired visual acuity is common in older adults, effective treatments are available for common causes of impaired visual acuity, and vision impairment can be identified noninvasively using the Snellen or other visual acuity chart. However, direct evidence found that vision screening in older adults in primary care settings is not effective for improving visual acuity or other clinical outcomes.
Contents
- 1. Introduction
- 2. Methods
- 3. Results
- Key Question 1 Does Vision Screening in Asymptomatic Older Adults Result in Improved Vision, Morbidity or Mortality, Quality of Life, Functional Status, or Cognition?
- Key Question 2 Are There Harms Associated With Vision Screening in Asymptomatic Older Adults?
- Key Question 3 What Is the Accuracy of Screening for Early Impairment in Visual Acuity Due to Uncorrected Refractive Error, Cataracts, or AMD?
- Key Question 4 Does Treatment of Early Impairment in Visual Acuity Due to Uncorrected Refractive Error, Cataracts, or AMD Lead to Improved Morbidity or Mortality or Quality of Life?
- Key Question 5 Are There Harms Associated With Treating Early Impairment in Visual Acuity Due to Uncorrected Refractive Error, Cataracts, or AMD?
- Contextual Question What Is a Clinically Meaningful Difference in Visual Acuity?
- 4. Discussion
- References
- Appendix A Detailed Methods
- Appendix B Evidence Tables From Prior USPSTF Review
- Appendix C Evidence and Quality Tables of Published Studies From This Update
- Appendix D Appendix Figures
Acknowledgements: The authors acknowledge AHRQ Medical Officer Tracy Wolff, MD, MPH; as well as current and former members of the U.S. Preventive Services Task Force who contributed to topic deliberations.
Prepared for: Agency for Healthcare Research and Quality, U.S. Department of Health and Human Services1, Contract No. HHSA-290-2012-0001-5-I, Task Order No. 4, Prepared by: Pacific Northwest Evidence-Based Practice Center2
Suggested citation:
Chou R, Dana T, Bougatsos C, Grusing S, Blazina I. Screening for Impaired Visual Acuity in Older Adults: A Systematic Review to Update the 2009 U.S. Preventive Services Task Force Recommendation. Evidence Synthesis No. 127. AHRQ Publication No. 14-05209-EF-1. Rockville, MD: Agency for Healthcare Research and Quality; 2016.
This report is based on research conducted by the Pacific Northwest Evidence-based Practice Center (EPC) under contract to the Agency for Healthcare Research and Quality (AHRQ), Rockville, MD (HHSA-290-2012-0001-5-I, Task Order No. 4). The findings and conclusions in this document are those of the authors, who are responsible for its contents, and do not necessarily represent the views of AHRQ. Therefore, no statement in this report should be construed as an official position of AHRQ or of the U.S. Department of Health and Human Services.
The information in this report is intended to help health care decisionmakers—patients and clinicians, health system leaders, and policymakers, among others—make well-informed decisions and thereby improve the quality of health care services. This report is not intended to be a substitute for the application of clinical judgment. Anyone who makes decisions concerning the provision of clinical care should consider this report in the same way as any medical reference and in conjunction with all other pertinent information (i.e., in the context of available resources and circumstances presented by individual patients).
The final report may be used, in whole or in part, as the basis for development of clinical practice guidelines and other quality enhancement tools, or as a basis for reimbursement and coverage policies. AHRQ or U.S. Department of Health and Human Services endorsement of such derivative products may not be stated or implied.
None of the investigators has any affiliations or financial involvement that conflicts with the material presented in this report.
- 1
5600 Fishers Lane, Rockville, MD 20857; www
.ahrq.gov - 2
Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239; www
.ohsu.edu/epc
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