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National Clinical Guideline Centre (UK). Blood Transfusion. London: National Institute for Health and Care Excellence (NICE); 2015 Nov. (NICE Guideline, No. 24.)

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Blood Transfusion.

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Table 60Base case analysis results (probabilistic analysis), cost-effectiveness, moderate risk

AnalysisIncremental QALYs vs STIncremental costs vs STINMB at £20K(a)Probability most CE optionRank (95% CI)
ST£00%3 (2, 3)
ICS+PCS0.000£420-£4230%4 (4, 4)
PCS0.000-£108£11340%2 (1, 3)
TXA0.000-£169£17360%1 (1, 2)

Abbreviations: CI = confidence intervals; ICS = intra-operative cell salvage; INMB = incremental net monetary benefit; PCS = post-operative cell salvage; QALYs = quality adjusted life years; ST = standard treatment; TXA = tranexamic acid

a

INMB = NMB intervention A – NMB ST; Highest INMB = most cost-effective option at a £20,000 per QALY threshold; a negative INMB means that ST is more cost-effective than this option.

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