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Medical Eligibility Criteria for Contraceptive Use. 5th edition. Geneva: World Health Organization; 2015.

Cover of Medical Eligibility Criteria for Contraceptive Use

Medical Eligibility Criteria for Contraceptive Use. 5th edition.

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Selection criteria for the systematic review

Study designClinical trials, observational studies, case series and pharmacokinetic studies
PopulationWomen of reproductive age
InterventionHormonal contraception and antiretroviral therapy (ART)
ComparatorHormonal contraception and no ART; non-comparative studies examining changes in outcomes over time
OutcomeContraceptive hormone pharmacokinetics, contraceptive effectiveness (pregnancy, ovulation, ovarian activity, breakthrough bleeding), ARV pharmacokinetics, ARV effectiveness (HIV disease progression, viral load, CD4 count), and adverse effects of either the hormonal contraceptive or the ARV medication.

From: I, Development of the Medical eligibility criteria for contraceptive use, fifth edition

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