Given the potential for non-invasive methods to address some of the shortcomings associated with liver biopsy, the focus of this Rapid Response report is to review the diagnostic accuracy, clinical effectiveness, cost-effectiveness and evidence-based guidelines associated with non-invasive liver tests. The report is conducted in the context of diagnosing and monitoring liver fibrosis in adult patients with chronic hepatitis B or C. This report represents a pseudo update to a previous 2012 report that reviewed the clinical and cost-effectiveness evidence of diagnosis and monitoring of liver fibrosis among patients with chronic hepatitis C.
Disclaimer: The Rapid Response Service is an information service for those involved in planning and providing health care in Canada. Rapid responses are based on a limited literature search and are not comprehensive, systematic reviews. The intent is to provide a list of sources of the best evidence on the topic that CADTH could identify using all reasonable efforts within the time allowed. Rapid responses should be considered along with other types of information and health care considerations. The information included in this response is not intended to replace professional medical advice, nor should it be construed as a recommendation for or against the use of a particular health technology. Readers are also cautioned that a lack of good quality evidence does not necessarily mean a lack of effectiveness particularly in the case of new and emerging health technologies, for which little information can be found, but which may in future prove to be effective. While CADTH has taken care in the preparation of the report to ensure that its contents are accurate, complete and up to date, CADTH does not make any guarantee to that effect. CADTH is not liable for any loss or damages resulting from use of the information in the report.
