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Swedish Council on Health Technology Assessment (SBU): SBU Systematic Review Summaries [Internet].

Percutaneous Vertebroplasty and Balloon Kyphoplasty in Treating Painful Osteoporotic Vertebral Compression Fractures

Summary and conclusions
SBU Alert Report No. 2011-02

March 30, 2011

  • The scientific evidence is insufficient to determine if percutaneous vertebroplasty or balloon kyphoplasty yield better outcomes than nonsurgical strategies or placebo in treating symptomatic vertebral compression fractures due to osteoporosis.
  • Cement leakage is common with both methods. Al­­though it usually causes no symptoms, the clin­ic­­al significance of such leakage is not fully investigated.
  • The scientific evidence is insufficient to determine the cost-effectiveness of percutaneous vertebroplasty and balloon kyphoplasty.
  • Randomised and blinded trials should be conducted, but such trials are associated with substantial methodological problems. Long-term evaluation of the methods’ effects and risks would require systematic follow-up, e.g. via a national quality registry.

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Copyright © 2011 by the Swedish Council on Health Technology Assessment. All content unless otherwise noted is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Bookshelf ID: NBK298986, PMID: 26153594

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