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Dretzke J, Riley RD, Lordkipanidzé M, et al. The prognostic utility of tests of platelet function for the detection of ‘aspirin resistance’ in patients with established cardiovascular or cerebrovascular disease: a systematic review and economic evaluation. Southampton (UK): NIHR Journals Library; 2015 May. (Health Technology Assessment, No. 19.37.)

Cover of The prognostic utility of tests of platelet function for the detection of ‘aspirin resistance’ in patients with established cardiovascular or cerebrovascular disease: a systematic review and economic evaluation

The prognostic utility of tests of platelet function for the detection of ‘aspirin resistance’ in patients with established cardiovascular or cerebrovascular disease: a systematic review and economic evaluation.

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Appendix 2Search strategies for economic studies

Database: MEDLINE (Ovid) (1946 to April week 4, 2012)

  1. ((ASA or aspirin or acetylsalicylic or anti platelet or antiplatelet or anti-platelet) adj2 (respons$ or non-respons$ or respond$ or non-respond$ or resistance or resist$)).mp.
  2. (platelet adj (response or respond$ or reactivity)).mp.
  3. 1 or 2
  4. exp Aspirin/
  5. exp Drug Resistance/
  6. 4 and 5
  7. 3 or 6
  8. (platelet function adj (analys$ or analyz$)).mp.
  9. (platelet function adj (assay$ or test$)).mp.
  10. Platelet Function Tests/
  11. PFA-100.mp.
  12. PlateletWorks.mp.
  13. Platelet Mapping.mp.
  14. Impact Cone.mp.
  15. platelet analyser$.mp.
  16. platelet analyzer$.mp.
  17. multiplate.mp.
  18. aggregometry.mp.
  19. LTA.mp.
  20. AA-induced LTA.mp.
  21. lumiaggregometry.mp.
  22. WBA.mp.
  23. ULTEGRA assay.mp.
  24. Impact-R.mp.
  25. TRAP-6.mp.
  26. TEG.mp.
  27. s-TEG.mp.
  28. thromboelastometry.mp.
  29. ROTEM.mp.
  30. VerifyNow.mp.
  31. Verify-Now.mp.
  32. VN-RPFA.mp.
  33. VASP.mp.
  34. VASP-P.mp.
  35. platelet reactivity index.mp.
  36. vasodilator-stimulated phosphoprotein phosphorylation assay$.mp.
  37. T-Guide.tw.
  38. T Guide.ti,ab.
  39. xylum clot signature analyser.mp.
  40. xylum clot signature analyzer.mp.
  41. ASA test$.mp.
  42. ASA assay$.mp.
  43. AA-induced LTA.mp.
  44. exp Platelet Count/ or platelet counting.mp.
  45. thrombelastography.mp. or Thrombelastography/
  46. thrombotic status analyser$.mp.
  47. thrombotic status analyzer$.mp.
  48. or/8-47
  49. exp Cardiovascular Diseases/
  50. exp Cerebrovascular Disorders/
  51. exp Diabetes Mellitus/
  52. or/49-51
  53. 48 and 52
  54. (predict$ or prognos$).mp.
  55. 48 and 54
  56. 7 or 53
  57. 7 or 55
  58. 56 or 57
  59. economics/
  60. exp “costs and cost analysis”/
  61. cost of illness/
  62. exp health care costs/
  63. economic value of life/
  64. exp economics medical/
  65. exp economics hospital/
  66. economics pharmaceutical/
  67. exp "fees and charges"/
  68. (econom$ or cost or costs or costly or costing or price or pricing or pharmacoeconomic$).tw.
  69. (expenditure$ not energy).tw.
  70. (value adj1 money).tw.
  71. budget$.tw.
  72. decision support techniques/
  73. markov.mp.
  74. exp models economic/
  75. decision analysis.mp.
  76. cost benefit analysis/
  77. or/59-76
  78. 58 and 77

Database: EMBASE (Ovid) (1980 to week 17, 2012)

  1. ((ASA or aspirin or acetylsalicylic or anti platelet or antiplatelet or anti-platelet) adj2 (respons$ or non-respons$ or respond$ or non-respond$ or resistance or resist$)).mp.
  2. (platelet adj (response or respond$ or reactivity)).mp.
  3. 1 or 2
  4. exp acetylsalicylic acid/
  5. exp drug resistance/
  6. 4 and 5
  7. 3 or 6
  8. (platelet function adj (analys$ or analyz$)).mp.
  9. (platelet function adj (assay$ or test$)).mp.
  10. PFA-100.mp.
  11. PlateletWorks.mp.
  12. Platelet Mapping.mp.
  13. Impact Cone.mp.
  14. platelet analyser$.mp.
  15. platelet analyzer$.mp.
  16. multiplate.mp.
  17. aggregometry.mp.
  18. LTA.mp.
  19. AA-induced LTA.mp.
  20. lumiaggregometry.mp.
  21. WBA.mp.
  22. ULTEGRA assay.mp.
  23. Impact-R.mp.
  24. TRAP-6.mp.
  25. TEG.mp.
  26. s-TEG.mp.
  27. thromboelastometry.mp.
  28. ROTEM.mp.
  29. VerifyNow.mp.
  30. Verify-Now.mp.
  31. VN-RPFA.mp.
  32. VASP.mp.
  33. VASP-P.mp.
  34. platelet reactivity index.mp.
  35. vasodilator-stimulated phosphoprotein phosphorylation assay$.mp.
  36. T Guide.mp.
  37. T Guide.mp.
  38. xylum clot signature analy$.mp.
  39. ASA tests$.mp.
  40. ASA assay$.mp.
  41. AA-induced LTA.mp.
  42. platelet counting.mp.
  43. thrombelastography.mp. or exp thromboelastography/
  44. thrombotic status analy$.mp.
  45. or/8-44
  46. exp cardiovascular disease/
  47. exp cerebrovascular disease/
  48. exp diabetes mellitus/
  49. or/46-48
  50. 45 and 49
  51. (predict$ or prognos$).mp
  52. 45 and 51
  53. 7 or 50
  54. 7 or 52
  55. 53 or 54
  56. cost benefit analysis/
  57. cost effectiveness analysis/
  58. cost minimization analysis/
  59. cost utility analysis/
  60. economic evaluation/
  61. (cost or costs or costed or costly or costing).tw.
  62. (economic$ or pharmacoeconomic$ or price$ or pricing).tw.
  63. (technology adj assessment$).tw.
  64. decision support.mp.
  65. markov.mp.
  66. exp statistical model/
  67. decision analysis.mp.
  68. exp “cost benefit analysis”/
  69. or/56-68
  70. 55 and 69

Database: The Cochrane Library (Wiley) (NHS Economic Evaluation Database) (2012, issue 2 of 4)

(Search date 4 May 2012.)

#1 (ASA or aspirin or acetylsalicylic or anti next platelet or antiplatelet) near/2 (respon* or non next respon* or resist*)

#2 (platelet) near/1 (response or respond* or reactivity)

#3 (#1 OR #2)

#4 MeSH descriptor Aspirin explode all trees

#5 MeSH descriptor Drug Resistance explode all trees

#6 (#4 AND #5)

#7 (#3 OR #6)

#8 (platelet function) near/1 (analys* or analyz*)

#9 (platelet function) near/1 (assay* or test*)

#10 PFA-100

#11 PlateletWorks

#12 Platelet next Mapping

#13 Cone

#14 platelet next analy*

#15 multiplate

#16 aggregometry

#17 LTA

#18 lumiaggregometry

#19 WBA

#20 ULTEGRA

#21 Impact-R

#22 TRAP-6

#23 TEG

#24 thromboelastometry

#25 ROTEM

#26 VerifyNow

#27 Verify-Now

#28 VN-RPFA

#29 VASP

#30 VASP-P

#31 platelet next reactivity next index

#32 vasodilator next stimulated next phosphoprotein

#33 T next Guide

#34 xylum next clot

#35 (ASA) next (test* or assay*)

#36 AA next induced

#37 platelet next counting

#38 thromboelastography

#39 thrombotic next status next analy*

#40 (#8 OR #9 OR #10 OR #11 OR #12 OR #13 OR #14 OR #15 OR #16 OR #17 OR #18 OR #19 OR #20 OR #21 OR #22 OR #23 OR #24 OR #25 OR #26 OR #27 OR #28 OR #29 OR #30 OR #31 OR #32 OR #33 OR #34 OR #35 OR #36 OR #37 OR #38 OR #39)

#41 MeSH descriptor Cardiovascular Diseases explode all trees

#42 MeSH descriptor Cerebrovascular Disorders explode all trees

#43 MeSH descriptor Diabetes Mellitus explode all trees

#44 (#41 OR #42 OR #43)

#45 (#40 AND #44)

#46 predict* or prognos*

#47 (#40 AND #46)

#48 (#7 OR #45)

#49 (#7 OR #47)

#50 (#48 OR #49)

Copyright © Queen’s Printer and Controller of HMSO 2015. This work was produced by Dretzke et al. under the terms of a commissioning contract issued by the Secretary of State for Health. This issue may be freely reproduced for the purposes of private research and study and extracts (or indeed, the full report) may be included in professional journals provided that suitable acknowledgement is made and the reproduction is not associated with any form of advertising. Applications for commercial reproduction should be addressed to: NIHR Journals Library, National Institute for Health Research, Evaluation, Trials and Studies Coordinating Centre, Alpha House, University of Southampton Science Park, Southampton SO16 7NS, UK.

Included under terms of UK Non-commercial Government License.

Bookshelf ID: NBK294168

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