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Rapid detection of health-care-associated bloodstream infection in critical care using multipathogen real-time polymerase chain reaction technology: a diagnostic accuracy study and systematic review.
Warhurst G, Dunn G, Chadwick P, et al.
Southampton (UK): NIHR Journals Library; 2015 May. (Health Technology Assessment, No. 19.35.)
Table of contents
Chapter 4, Challenging the assumption that laboratory-confirmed diagnosis of bloodstream infection is an error-free gold standard: statistical modelling using latent class analysis.
Chapter 3, Clinical diagnostic accuracy study of rapid detection of sepsis-related health-care-associated bloodstream infection in intensive care using SeptiFast multipathogen real-time polymerase chain reaction technology.
Chapter 1, Background and rationale.
Scientific summary.
Appendix 16, Latent class/finite mixture model specification in Mplus.
Chapter 2, Accuracy of LightCycler SeptiFast real-time polymerase chain reaction for the detection and identification of pathogens in the blood of patients with suspected sepsis: a systematic review and meta-analysis.
Chapter 5, Conclusions and recommendations.
Appendix 2, Search strategy for the systematic review.
Appendix 8, Participant information sheet: recovered capacity.
List of abbreviations.
Appendix 3, Quality assessment of diagnostic accuracy studies methodology table.
Appendix 6, Participant information sheet: capacity at study commencement.
Appendix 7, Participant consent form: capacity at study commencement.
Appendix 5, Consultee declaration form.
Appendix 4, Consultee information sheet.
Appendix 11, Completing the laboratory case record form.
Plain English summary.
Appendix 14, SeptiFast assay: data analysis and reporting.
Acknowledgements.
References.
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