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Excerpt
Following the success of liver transplantation in children from living donors, many transplant centers have begun performing the procedure in adults. Living donor transplantation represents a major advance in the efforts to relieve the growing national shortage of cadaveric organs.
Donation to adults usually requires a right hepatic lobectomy, a procedure that has been associated with greater morbidity compared to the left lateral segmentectomy typically used for donation to children. A variety of complications related to right hepatic lobe donation have been described, including deaths. However, the frequency and nature of complications are incompletely understood. Thus, the purpose of this evidence report is to summarize the available evidence regarding the outcomes of donors who participated in right lobe donation for adult LDLT
Contents
Submitted to: Agency for Healthcare Research and Quality, 6010 Executive Boulevard, Suite 300, Rockville, Maryland 20852; Submitted by: New England Medical Center Evidence Practice Center, Boston, Massachusetts
- Safety of donor in adult-to-adult living donor liver transplantation using right lobe graft.[Transplant Proc. 2007]Safety of donor in adult-to-adult living donor liver transplantation using right lobe graft.Jiang XZ, Yan LN, Li B, Wen TF, Zeng Y, Wang WT, Zhao JC, Yang JY, Xu MQ, Ma YK, et al. Transplant Proc. 2007 Jan-Feb; 39(1):150-2.
- Dual left lobe living donor liver transplantation using donors unacceptable for right lobe donation: a case report.[Transplant Proc. 2010]Dual left lobe living donor liver transplantation using donors unacceptable for right lobe donation: a case report.Dayangac M, Taner CB, Akin B, Uraz S, Balci D, Duran C, Ayanoglu O, Killi R, Yuzer Y, Tokat Y. Transplant Proc. 2010 Dec; 42(10):4560-3.
- Complications and long-term outcome of living liver donors: a survey of 1,508 cases in five Asian centers.[Transplantation. 2003]Complications and long-term outcome of living liver donors: a survey of 1,508 cases in five Asian centers.Lo CM. Transplantation. 2003 Feb 15; 75(3 Suppl):S12-5.
- Review Long-term complications of living donor liver transplantation.[Liver Transpl. 2000]Review Long-term complications of living donor liver transplantation.Renz JF, Roberts JP. Liver Transpl. 2000 Nov; 6(6 Suppl 2):S73-6.
- Review Living-donor liver transplantation for high-urgency situations.[Transplantation. 2003]Review Living-donor liver transplantation for high-urgency situations.Liu CL, Fan ST, Lo CM, Wong J. Transplantation. 2003 Feb 15; 75(3 Suppl):S33-6.
- Morbidity and Mortality Among Adult Living Donors Undergoing Right Hepatic Lobec...Morbidity and Mortality Among Adult Living Donors Undergoing Right Hepatic Lobectomy for Adult Recipients
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