NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.
This publication is provided for historical reference only and the information may be out of date.
Negative Pressure Wound Therapy Technologies for Chronic Wound Care in the Home Setting
Technology Assessment Report
Susan M Rhee, MD, M Frances Valle, DNP, MS, Lisa M Wilson, ScM, Gerald Lazarus, MD, Jonathan M Zenilman, MD, and Karen A Robinson, PhD.
Author Information and AffiliationsStructured Abstract
Objectives:
To systematically review the efficacy and safety of negative pressure wound therapy (NPWT) for treatment of chronic wounds in the home setting.
Data Sources:
On June 2014, we searched MEDLINE®, Embase®, the Cochrane Central Register of Controlled Trials, and the Cumulative Index to Nursing and Allied Health Literature (CINAHL®).
Review Methods:
Two independent reviewers screened search results. We included studies examining the use of NPWT in patients with chronic wounds, including venous leg ulcers, arterial leg ulcers, diabetic foot ulcers, pressure ulcers, and mixed etiology chronic wounds. We searched for comparative trials that followed subjects in the home setting. We extracted data into standardized forms and summarized results qualitatively.
Results:
We retrieved 5,912 citations, and found seven studies which met our criteria for inclusion. Six of the studies compared NPWT devices to other wound care methods. One study compared two different NPWT devices. Data were limited by variability in the types of comparator groups, variable quality in study design, and limited reporting of outcomes.
Conclusions:
We were unable to draw conclusions about the efficacy or safety of NPWT for the treatment of chronic wounds in the home setting due to insufficient evidence. Though NPWT has been used across the wound care spectrum, significant research gaps remain. Standardization of wound care research protocols, such as providing consistency in comparator groups, robust randomized study designs, larger trials, and common definitions of outcomes, would be helpful in providing evidence to inform decisions about the use of NPWT.
Contents
- Acknowledgments
- Introduction
- Methods
- Results
- Search Results
- Negative Pressure Wound Therapy Technologies Commercially Available in the U.S.
- Home Use of Negative Pressure Wound Therapy Compared With Other Wound Care Methods
- Wound Care Modalities Used Prior To Or With Intervention
- Characteristics of Negative Pressure Wound Therapy Compared With Other Characteristics
- Discussion
- References
- List of Abbreviations
- Appendix A Detailed Electronic Database Search Strategies
- Appendix B Forms
- Appendix C List of Excluded Studies
- Appendix D Evidence Tables
Suggested citation:
Rhee SM, Valle MF, Wilson LM, Lazarus G, Zenilman J, Robinson KA. Negative Pressure Wound Therapy Technologies For Chronic Wound Care in the Home Setting. Evidence Report/Technology Assessment. (Prepared by the Johns Hopkins University Evidence-based Practice Center under Contract No. 290-201-200007-I.) Rockville, MD: Agency for Healthcare Research and Quality. August 2014. www.ahrq.gov.
This report is based on research conducted by the Johns Hopkins University Evidence-based Practice Center under contract to the Agency for Healthcare Research and Quality (AHRQ), Rockville, MD (HHSA 290-201-200007-I). The findings and conclusions in this document are those of the author(s) who are responsible for its contents; the findings and conclusions do not necessarily represent the views of AHRQ. No statement in this article should be construed as an official position of the Agency for Healthcare Research and Quality or of the U.S. Department of Health and Human Services.
The information in this report is intended to help health care decision-makers; patients and clinicians, health system leaders, and policymakers, make well-informed decisions and thereby improve the quality of health care services. This report is not intended to be a substitute for the application of clinical judgment. Decisions concerning the provision of clinical care should consider this report in the same way as any medical reference and in conjunction with all other pertinent information, i.e., in the context of available resources and circumstances presented by individual patients.
This report may be used, in whole or in part, as the basis for development of clinical practice guidelines and other quality enhancement tools, or as a basis for reimbursement and coverage policies. AHRQ or U.S. Department of Health and Human Services endorsement of such derivative products may not be stated or implied.
None of the investigators has any affiliations or financial involvement related to the material presented in this report.
- Review Negative pressure wound therapy technologies for chronic wound care in the home setting: A systematic review.[Wound Repair Regen. 2015]Review Negative pressure wound therapy technologies for chronic wound care in the home setting: A systematic review.Rhee SM, Valle MF, Wilson LM, Lazarus G, Zenilman JM, Robinson KA. Wound Repair Regen. 2015 Jul-Aug; 23(4):506-17. Epub 2015 Jul 31.
- Review Systematic reviews of wound care management: (3) antimicrobial agents for chronic wounds; (4) diabetic foot ulceration.[Health Technol Assess. 2000]Review Systematic reviews of wound care management: (3) antimicrobial agents for chronic wounds; (4) diabetic foot ulceration.O'Meara S, Cullum N, Majid M, Sheldon T. Health Technol Assess. 2000; 4(21):1-237.
- Review Negative pressure wound therapy: a vacuum of evidence?[Arch Surg. 2008]Review Negative pressure wound therapy: a vacuum of evidence?Gregor S, Maegele M, Sauerland S, Krahn JF, Peinemann F, Lange S. Arch Surg. 2008 Feb; 143(2):189-96.
- Review Chronic Venous Ulcers: A Comparative Effectiveness Review of Treatment Modalities[ 2013]Review Chronic Venous Ulcers: A Comparative Effectiveness Review of Treatment ModalitiesZenilman J, Valle MF, Malas MB, Maruthur N, Qazi U, Suh Y, Wilson LM, Haberl EB, Bass EB, Lazarus G. 2013 Dec
- Review Screening for High Blood Pressure in Adults: A Systematic Evidence Review for the U.S. Preventive Services Task Force[ 2014]Review Screening for High Blood Pressure in Adults: A Systematic Evidence Review for the U.S. Preventive Services Task ForcePiper MA, Evans CV, Burda BU, Margolis KL, O’Connor E, Smith N, Webber E, Perdue LA, Bigler KD, Whitlock EP. 2014 Dec
- Negative Pressure Wound Therapy Technologies for Chronic Wound Care in the Home ...Negative Pressure Wound Therapy Technologies for Chronic Wound Care in the Home Setting
Your browsing activity is empty.
Activity recording is turned off.
See more...