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Chou R, Hashimoto R, Friedly J, et al. Pain Management Injection Therapies for Low Back Pain [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2015.

  • This publication is provided for historical reference only and the information may be out of date.

This publication is provided for historical reference only and the information may be out of date.

Cover of Pain Management Injection Therapies for Low Back Pain

Pain Management Injection Therapies for Low Back Pain [Internet].

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Table 8Pooled results of epidural corticosteroid injections versus placebo interventions for spinal stenosis

OutcomeEstimate (95% CI)Number of TrialsI2
Pain, mean improvement (WMD)a
    • Immediate-term followup−22.0 (−36.0 to −8.00)1120--
    • Short-term followup0.62 (−2.87 to 4.11)5117, 120, 122, 123, 1260%
    • Intermediate-term followup3.73 (−0.81 to 8.26)3122, 1230%
    • Long-term followup4.00 (−2.87 to 10.9)1123--
Pain successful outcome (RR)
    • Short-term followup0.98 (0.84 to 1.15)3117, 122, 1230%
    • Intermediate-term followup0.98 (0.78 to 1.24)2122, 1230%
    • Long-term followup0.97 (0.74 to 1.28)366, 122, 1230%
Function, mean improvement
    • Immediate-term followup (SMD)−0.32 (−0.85 to 0.22)2120, 1260%
    • Short-term followup (SMD)−0.03 (−0.31 to 0.26)5117, 120, 122, 123, 12660%
    • Intermediate-term followup (WMD) a2.81 (−0.44 to 6.06)3120, 122, 1230%
    • Long-term followup (WMD) a2.78 (−1.24 to 6.79)2122, 1230%
Function, successful outcome (RR)
    • Short-term followup0.91 (0.70 to 1.18)3117, 122, 12337%
    • Intermediate-term followup0.96 (0.74 to 1.25)2122, 1230%
    • Long-term followup0.95 (0.71 to 1.26)2122, 1230%
Surgery (RR)
    • Long-term followup0.76 (0.38 to 1.54)1115--
Successful outcome (RR)
    • Short-term followup1.18 (0.55 to 2.55)2123, 12680%
    • Intermediate-term followup0.93 (0.63 to 1.35)1123--
    • Long-term followup1.16 (0.76 to 1.78)2115, 1230%

RR=relative risk; SMD=standardized mean difference; WMD=weighted mean difference

a

0 to 100 scale

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