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Chou R, Hashimoto R, Friedly J, et al. Pain Management Injection Therapies for Low Back Pain [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2015.
This publication is provided for historical reference only and the information may be out of date.
Table 8Pooled results of epidural corticosteroid injections versus placebo interventions for spinal stenosis
Outcome | Estimate (95% CI) | Number of Trials | I2 |
---|---|---|---|
Pain, mean improvement (WMD)a | |||
• Immediate-term followup | −22.0 (−36.0 to −8.00) | 1120 | -- |
• Short-term followup | 0.62 (−2.87 to 4.11) | 5117, 120, 122, 123, 126 | 0% |
• Intermediate-term followup | 3.73 (−0.81 to 8.26) | 3122, 123 | 0% |
• Long-term followup | 4.00 (−2.87 to 10.9) | 1123 | -- |
Pain successful outcome (RR) | |||
• Short-term followup | 0.98 (0.84 to 1.15) | 3117, 122, 123 | 0% |
• Intermediate-term followup | 0.98 (0.78 to 1.24) | 2122, 123 | 0% |
• Long-term followup | 0.97 (0.74 to 1.28) | 366, 122, 123 | 0% |
Function, mean improvement | |||
• Immediate-term followup (SMD) | −0.32 (−0.85 to 0.22) | 2120, 126 | 0% |
• Short-term followup (SMD) | −0.03 (−0.31 to 0.26) | 5117, 120, 122, 123, 126 | 60% |
• Intermediate-term followup (WMD) a | 2.81 (−0.44 to 6.06) | 3120, 122, 123 | 0% |
• Long-term followup (WMD) a | 2.78 (−1.24 to 6.79) | 2122, 123 | 0% |
Function, successful outcome (RR) | |||
• Short-term followup | 0.91 (0.70 to 1.18) | 3117, 122, 123 | 37% |
• Intermediate-term followup | 0.96 (0.74 to 1.25) | 2122, 123 | 0% |
• Long-term followup | 0.95 (0.71 to 1.26) | 2122, 123 | 0% |
Surgery (RR) | |||
• Long-term followup | 0.76 (0.38 to 1.54) | 1115 | -- |
Successful outcome (RR) | |||
• Short-term followup | 1.18 (0.55 to 2.55) | 2123, 126 | 80% |
• Intermediate-term followup | 0.93 (0.63 to 1.35) | 1123 | -- |
• Long-term followup | 1.16 (0.76 to 1.78) | 2115, 123 | 0% |
RR=relative risk; SMD=standardized mean difference; WMD=weighted mean difference
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- Table 8, Pooled results of epidural corticosteroid injections versus placebo int...Table 8, Pooled results of epidural corticosteroid injections versus placebo interventions for spinal stenosis - Pain Management Injection Therapies for Low Back Pain
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