U.S. flag

An official website of the United States government

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.

Feingold KR, Anawalt B, Blackman MR, et al., editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-.

Cover of Endotext

Endotext [Internet].

Show details
Figure 9. . Schematic model demonstrating the interaction and activity of HAT coactivators and other chromatin modulators, which are attracted by GR to the promoter region of glucocorticoid-responsive genes.

Figure 9.

Schematic model demonstrating the interaction and activity of HAT coactivators and other chromatin modulators, which are attracted by GR to the promoter region of glucocorticoid-responsive genes. Promoter-associated GR is cleared by the ubiquitin-proteasomal pathway, which regulates turnover of GR on DNA. Modified from (82). AF-1 and -2: activation function-1 and -2; CBP: cAMP-responsive element-binding protein (CREB)-binding protein; DRIP: vitamin D receptor-interacting protein; GREs: glucocorticoid response elements; p/CAF: p300/CBP-associated factor; SWI/SNF: mating-type switching/sucrose non-fermenting; TRAP: thyroid hormone receptor-associated protein.

From: Glucocorticoid Receptor

Copyright © 2000-2024, MDText.com, Inc.

This electronic version has been made freely available under a Creative Commons (CC-BY-NC-ND) license. A copy of the license can be viewed at http://creativecommons.org/licenses/by-nc-nd/2.0/.

Views

  • Cite this Page

Similar articles in PubMed

See reviews...See all...

Recent Activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...