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Feingold KR, Anawalt B, Blackman MR, et al., editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-.
Schematic model demonstrating the interaction and activity of HAT coactivators and other chromatin modulators, which are attracted by GR to the promoter region of glucocorticoid-responsive genes. Promoter-associated GR is cleared by the ubiquitin-proteasomal pathway, which regulates turnover of GR on DNA. Modified from (82). AF-1 and -2: activation function-1 and -2; CBP: cAMP-responsive element-binding protein (CREB)-binding protein; DRIP: vitamin D receptor-interacting protein; GREs: glucocorticoid response elements; p/CAF: p300/CBP-associated factor; SWI/SNF: mating-type switching/sucrose non-fermenting; TRAP: thyroid hormone receptor-associated protein.
From: Glucocorticoid Receptor
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