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Feingold KR, Anawalt B, Blackman MR, et al., editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-.

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Table 22.

Advantages and Disadvantages of DPP-4 Inhibitors

AdvantagesDisadvantages
No hypoglycemiaPancreatic disease
Weight neutralHeart failure (saxagliptin/alogliptin)?
Decreases postprandial glucoseArthritis
Once a dayBullous pemphigoid
Well toleratedRelatively expensive
Decreases BPModest glycemic lowering

From: Oral and Injectable (Non-Insulin) Pharmacological Agents for the Treatment of Type 2 Diabetes

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