Figure 4. Transcription factor network in endoderm induction.

Figure 4Transcription factor network in endoderm induction.

Grey arrows show inductions. Black is used when direct regulation was demonstrated. Red lines show molecular interactions. Some of the regulations have not been demonstrated in mice and may come from Zebrafish or Xenopus. Mix, Sox17 and Gatas each regulate a subset of differentiation genes (Sinner et al., 2006).

From: Endoderm specification

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StemBook [Internet].
Cambridge (MA): Harvard Stem Cell Institute; 2008-.
Copyright: © 2008 Anne Grapin-Botton.

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