Contents

• INSTITUTE OF MEDICINE: Division of Health Care Services HCFA Effectiveness Initiative: Acute Myocardial Infarction Workshop Committee
• Acknowledgments
• Summary
• Introduction
• The Knowledge Base for Key Clinical Issues in Acute Myocardial Infraction
  • Etiology
  • Epidemiology
  • Diagnosis and Management
  • Therapeutic Options
• Factors Important for the Selection of Key Patient Management Issues and Related Research Activities
  • Selecting Patient Management Issues
  • Selecting Research Topics and Activities
• Key Patient Management Topics for Effectiveness Research in Acute Myocardial Infraction
  • Preliminary Discussion and Selection of Major Topics
  • Summary of Recommendations
  • Methods Issues
  • Patient Management Topics
• Conclusions
• Bibliography
• Appendix A Background and Conduct of the Workshop

This workshop was supported by the Health Care Financing Administration, U.S. Department of Health and Human Services, under Basic Ordering Agreement Contract No. 500-89-0008.

NOTICE: The project that is the subject of this report was approved by the Governing Board of the National Research Council, whose members are drawn from the councils of the National Academy of Sciences, the National Academy of Engineering, and the Institute of Medicine. The members of the committee responsible for this report were chosen for their special competencies and with regard for appropriate balance.

The report has been reviewed by a group other than the authors according to procedures approved by a Report Review Committee consisting of members of the National Academy of Sciences, the National Academy of Engineering, and the Institute of Medicine.

The Institute of Medicine was chartered in 1970 by the National Academy of Sciences to enlist distinguished members of the appropriate professions in the examination of policy matters pertaining to the health of the public. In this, the Institute acts under both the Academy's 1863 congressional charter responsibility to be an adviser to the federal government and its own initiative in identifying issues of medical care, research, and education.