Figure 124.2. FAB M0.

Figure 124.2

FAB M0. Marrow blasts from patients with this undifferentiated type of acute myelogenous leukemia can have variable amounts of agranular cytoplasms with Auer rods. Cells are peroxidase- and Sudan black-negative and can be confused with FAB M7 or FAB L2. Myeloid commitment of these blasts can be confirmed by immunophenotyping with antibodies against myeloid antigens and/or demonstration of ultrastructural peroxidase-positive granules using transmission electron microscopy.

From: Chapter 124, Acute Myeloid Leukemia in Adults

Cover of Holland-Frei Cancer Medicine
Holland-Frei Cancer Medicine. 5th edition.
Bast RC Jr, Kufe DW, Pollock RE, et al., editors.
Hamilton (ON): BC Decker; 2000.
© 2000, BC Decker Inc.

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