Figure 13.6. A diagram demonstrating the sites of activity of the gene products of the candidate genes in the polygenic model.

Figure 13.6

A diagram demonstrating the sites of activity of the gene products of the candidate genes in the polygenic model. Chol = cholesterol; DHT = dihydrotestosterone; HSD3ß1 = 3ß-hydroxysteroid dehydrogenase I; HSD3ß2 = 3ß-hydroxysteroid dehydrogenase II; HSD3α = 3α-hydroxysteroid dehydrogenase; HSD17B3 = 17 ß-hydroxysteroid dehydrogenase type III; LH Rec = luteinizing hormone receptor; SRD5A2 = steroid 5α-reductase type II; T, testosterone.

From: Chapter 13, Hormones and the Etiology of Cancer

Cover of Holland-Frei Cancer Medicine
Holland-Frei Cancer Medicine. 5th edition.
Bast RC Jr, Kufe DW, Pollock RE, et al., editors.
Hamilton (ON): BC Decker; 2000.
© 2000, BC Decker Inc.

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