FIGURE 8.5. Glia/neuron ratio scales differently across structures and orders with structure mass, but scales homogeneously with neuronal density.

FIGURE 8.5

Glia/neuron ratio scales differently across structures and orders with structure mass, but scales homogeneously with neuronal density. Each point represents the average other cell/neuron ratio (which approximates the glia/neuron ratio) and structure mass (A) or neuronal density (B) in the cerebral cortex (circles), cerebellum (squares), or RoB (triangles) of a species (insectivores, filled gray symbols; rodents, filled black symbols; primates, open black symbols; scandentia, open gray symbols). Notice that in contrast to the scattered distribution across species and structures in (A), datapoints are aligned across species and structures in the bottom plot, suggesting that it is smaller neuronal densities (i.e., larger average neuronal cell size), not larger structure mass, that is accompanied by a larger glia/neuron ratio. Data from Herculano-Houzel et al. (2006, 2007, 2011), Azevedo et al. (2009), Sarko et al. (2009), and Gabi et al. (2010).

From: 8, The Remarkable, Yet Not Extraordinary, Human Brain as a Scaled-Up Primate Brain and Its Associated Cost

Cover of In the Light of Evolution
In the Light of Evolution: Volume VI: Brain and Behavior.
National Academy of Sciences; Striedter GF, Avise JC, Ayala FJ, editors.
Washington (DC): National Academies Press (US); 2013 Jan 25.
Copyright 2013 by the National Academy of Sciences. All rights reserved.

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