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Henderson JT, Whitlock EP, O'Conner E, et al. Low-Dose Aspirin for the Prevention of Morbidity and Mortality From Preeclampsia: A Systematic Evidence Review for the U.S. Preventive Services Task Force [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2014 Apr. (Evidence Syntheses, No. 112.)
This publication is provided for historical reference only and the information may be out of date.
Low-Dose Aspirin for the Prevention of Morbidity and Mortality From Preeclampsia: A Systematic Evidence Review for the U.S. Preventive Services Task Force [Internet].
Show detailsTable 7Number Needed to Treat for Three Levels of Risk for Preeclampsia, IUGR, and Preterm Birth
| Outcome | Risk of outcome | RR | Absolute change in risk | Risk after change | NNT Benefit (95% CI) | NNT Harm (95% CI) |
|---|---|---|---|---|---|---|
| Preeclampsia | 0.10 | 0.76 | -0.02 | 0.08 | 42 (26, 200) | NA |
| 0.18 | 0.76 | -0.04 | 0.14 | 23 (15, 111) | NA | |
| 0.23 | 0.76 | -0.06 | 0.17 | 18 (11, 87) | NA | |
| IUGR | 0.07 | 0.80 | -0.01 | 0.06 | 71 (41, 1429) | NA |
| 0.13 | 0.80 | -0.03 | 0.10 | 38 (22, 769) | NA | |
| 0.24 | 0.80 | -0.05 | 0.19 | 21 (12, 417) | NA | |
| Preterm birth | 0.11 | 0.86 | -0.02 | 0.09 | 65 (38, 455) | NA |
| 0.19 | 0.86 | -0.03 | 0.16 | 38 (22, 263) | NA | |
| 0.31 | 0.86 | -0.04 | 0.27 | 23 (13, 161) | NA | |
| Abruption (in women at increased risk) | 0.015 | 1.12 | 0.002 | 0.017 | NA | 556 (145 harm to ∞ to 476 benefit) |
| 0.020 | 1.12 | 0.002 | 0.022 | NA | 417 (109 harm to ∞ to 357 benefit) | |
| Abruption (across all risk levels) | 0.015 | 1.17 | 0.0026 | 0.018 | NA | 392 (139 harm to ∞ to 952 benefit) |
| 0.020 | 1.17 | 0.0034 | 0.023 | NA | 294 (104 harm to ∞ to 714 benefit) |
Abbreviations: IUGR = intrauterine growth restriction; NNT = number needed to treat; RR = relative risk.
- Table 7, Number Needed to Treat for Three Levels of Risk for Preeclampsia, IUGR,...Table 7, Number Needed to Treat for Three Levels of Risk for Preeclampsia, IUGR, and Preterm Birth - Low-Dose Aspirin for the Prevention of Morbidity and Mortality From Preeclampsia
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