NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.
Coffin JM, Hughes SH, Varmus HE, editors. Retroviruses. Cold Spring Harbor (NY): Cold Spring Harbor Laboratory Press; 1997.
Table 5Retroviruses Involved in CNS Disease
| Virus | Animal(s) affected | Types of disease | Latent period | Incidencea(%) | References |
|---|---|---|---|---|---|
| Cas-Br-E MLV | mice | spongiform encephalopathy | 1–8 months | 70–100 | Gardner et al. (1973); Gardner (1978); Portis (1990) |
| ts1 Mo-MLV | mice | spongiform encephalopathy | 1–2 months | 80–100 | Wong et al. (1983); Wong (1990) |
| ts-BA1 Mo-MLV | mice | spongiform encephalopathy | 2.5–5 months | 80–100 | Bilello et al. (1986) |
| PVC-211 | rats/mice | spongiform encephalopathy | 1 month | 100 | Kai and Furuta (1984) |
| NT40 MLV | rats | spongiform encephalopathy | 4–6 weeks | 100 | Czub et al. (1995) |
| FMCF98 | mice | astrocyte degeneration | 1–3 months | 100 | Portis et al. (1995) |
| TR1.3 MLV | mice | intracerebral hemorrhages | 3 weeks | 100 | Park et al. (1993) |
| HTLV-1 | humans | meningomyelitis | 2–30 years | <1 | Poiesz et al. (1980); Gessain and Gout (1992) |
| MVV | sheep/goats | encephalomyelitis | 2–5 years | <5 | Sigurdsson et al. (1957); Haase (1986) |
| CAEV | kid goats | encephalomyelitis | 1–6 months | 20 | Cork et al. (1974); McGuire et al. (1990) |
| FIV | cats | encephalopathy | 2–5 years | 5 | Pedersen et al. (1987); Pedersen (1993) |
| EIAV | horses | encephalomyelitis | unknown | sporadic | Vallee and Carre (1904); Montelaro et al. (1993) |
| SIV | primates | encephalopathy | <1 year | 50 | see Chapter 11 |
| HIV | humans | encephalopathy | 5–10 years | 25–65 | see Chapter 11 |
- a
The incidence of disease varies in many cases depending on the strain of animal infected and the titer of virus infecting the host.
(HTLV-1) Human T-cell leukemia virus type 1; (MVV) maedi/visna virus; (CAEV) caprine arthritis encephalitis virus; (FIV) feline immunodeficiency virus; (EIAV) equine infectious anemia virus; (SIV) simian immunodeficiency virus; (HIV) human immunodeficiency virus; (FMCF) Friend mink cell focus-forming virus.
- Table 5, Retroviruses Involved in CNS Disease - RetrovirusesTable 5, Retroviruses Involved in CNS Disease - Retroviruses
- Homo sapiens 3 BAC RP11-227J5 (Roswell Park Cancer Institute Human BAC Library) ...Homo sapiens 3 BAC RP11-227J5 (Roswell Park Cancer Institute Human BAC Library) complete sequencegi|21206011|gnl|bcmhgsc|project_hai lor|gb|AC024221.23|Nucleotide
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