Figure 2. . Fsr quorum sensing system in E.

Figure 2.

Fsr quorum sensing system in E. faecalis. The fsr locus consists of fsrABCD, which encode the proteins that are responsible for generating and sensing the peptide signal molecule. Once the critical concentration of GBAP is reached, the FsrC/A two-component system is activated, causing the transcriptional activation of fsrBCD and the downstream gene locus gelE/sprE, resulting in elevated expression of extracellular proteases GelE and SprE.

From: Transcriptional and Post Transcriptional Control of Enterococcal Gene Regulation

Cover of Enterococci
Enterococci: From Commensals to Leading Causes of Drug Resistant Infection [Internet].
Gilmore MS, Clewell DB, Ike Y, et al., editors.
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