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The National Institutes of Health (NIH) promotes advances in biomedical research primarily by supporting extramural research at colleges and universities and other nonprofit research institutions. Center awards are one mechanism of extramural support, constituting approximately 9 percent of NIH's budget. Centers are very diverse in structure and purpose, and definitions of centers and metrics for measuring their productivity are not uniformly applied across institutes, making it difficult to evaluate their effectiveness. The committee finds, however, that extramural centers offer an attractive mechanism for supporting research that benefits from a multidisciplinary, team-based approach, especially research aimed at understanding complex biomedical systems, and for translating basic scientific discoveries into useful clinical applications. The committee makes recommendations to improve the classification and tracking of center programs, clarify and improve the decision process and criteria for initiating center programs, resolve the occasional disagreements over the appropriateness of centers, and evaluate the performance of center programs more regularly and systematically. The report concludes by noting that recent changes in the nature of biomedical research, which involve opportunities to understand complex biological systems through collaborations among multiple investigators in different fields and different institutions and by assembling large-scale research infrastructures and databases, will probably result in the expanded use of centers and other mechanisms that support collaborative research by interdisciplinary teams.
Contents
- The National Academies
- Committee for Assessment of NIH Centers of Excellence Programs
- Independent Report Reviewers
- Preface
- Acronyms and Abbreviations
- Executive Summary
- 1. Introduction
- 2. Current Use of Center Awards
- 3. Initiation and Management of Center Programs
- 4. Criteria for Establishing Center Programs
- 5. Evaluation of Center Programs
- 6. Closing Comments and Thoughts About the Future
- Appendixes
- A. NIH Center Programs
- B. Biographical Sketches of Committee and Staff
- C. NIH Research Award Activity Codes and Their Definitions
- D. NIH Program Planning Process
- E. Justifications for Center Programs Used in Recent RFAs and PAs
- F. Summary of Selected Center Program Evaluations Previously Conducted by NIH
NOTICE: The project that is the subject of this report was approved by the Governing Board of the National Research Council, whose members are drawn from the councils of the National Academy of Sciences, the National Academy of Engineering, and the Institute of Medicine. The members of the committee responsible for the report were chosen for their special competences and with regard for appropriate balance.
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