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Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
Table 2Assays for the current probe discovery effort (ML302)
| AID | Assay Name | Assay Type | Target | Powder Sample |
|---|---|---|---|---|
| 624079 | Absorbance-based Biochemical Nitrocefin Substrate Hydrolysis Assays (IC50) | Dose Response (2X IC50) (probe ML302) | VIM-2 | Yes |
| 624085 | IMP-1 | Yes | ||
| 624092 | TEM-1 | Yes | ||
| 624090 | AmpC | Yes | ||
| 624083 | Absorbance-based Biochemical Nitrocefin Substrate Hydrolysis Assays (Ki and Km) | Dose Response (2X) | VIM-2 | Yes |
| 624084 | IMP-1 | Yes | ||
| 624096 | Absorbance based Imipenem Antibiotic Synergy Assay (MIC4X): YMC07/B3323 | Dose Response (2X) | VIM-2 | Yes |
| 624081 | Absorbance based Imipenem Antibiotic Synergy Assay (MIC4X): BL21 | Dose Response (2X) | VIM-2 | Yes |
| 624080 | Absorbance based Imipenem Antibiotic Synergy Assay (MIC4X): PA641 | Dose Response (2X) | VIM-2 | Yes |
| 624082 | Absorbance based Imipenem Antibiotic Synergy Assay (MIC4X): BAA-2146 | Dose Response (2X) | NDM-1 | Yes |
| 624095 | Absorbance based Imipenem Antibiotic Synergy Assay (MIC4X): KN20 | Dose Response (2X) | IMP-1 | Yes |
| 624097 | Absorbance based Imipenem Antibiotic Synergy Assay (MIC4X): BL21 | Dose Response (2X) | IMP-1 | Yes |
- PubChem SubstanceRelated PubChem Substances
- Review HTS Assay for Discovery of Novel Metallo-Beta-lactamase (MBL) Inhibitors.[Probe Reports from the NIH Mol...]Review HTS Assay for Discovery of Novel Metallo-Beta-lactamase (MBL) Inhibitors.Minond D, Saldanha SA, Spicer T, Qin L, Mercer BA, Roush WR, Hodder P. Probe Reports from the NIH Molecular Libraries Program. 2010
- Multiyear, Multinational Survey of the Incidence and Global Distribution of Metallo-β-Lactamase-Producing Enterobacteriaceae and Pseudomonas aeruginosa.[Antimicrob Agents Chemother. 2...]Multiyear, Multinational Survey of the Incidence and Global Distribution of Metallo-β-Lactamase-Producing Enterobacteriaceae and Pseudomonas aeruginosa.Kazmierczak KM, Rabine S, Hackel M, McLaughlin RE, Biedenbach DJ, Bouchillon SK, Sahm DF, Bradford PA. Antimicrob Agents Chemother. 2016 Feb; 60(2):1067-78. Epub 2015 Dec 7.
- Metallo-beta-lactamase-producing imipenem-resistant Pseudomonas aeruginosa clinical isolates in a university teaching hospital in Malaysia: detection of IMP-7 and first identification of IMP-4, VIM-2, and VIM-11.[Diagn Microbiol Infect Dis. 2010]Metallo-beta-lactamase-producing imipenem-resistant Pseudomonas aeruginosa clinical isolates in a university teaching hospital in Malaysia: detection of IMP-7 and first identification of IMP-4, VIM-2, and VIM-11.Khosravi Y, Tee Tay S, Vadivelu J. Diagn Microbiol Infect Dis. 2010 Jul; 67(3):294-6. Epub 2010 May 11.
- bla(IMP) and bla(VIM) mediated carbapenem resistance in Pseudomonas and Acinetobacter species in India.[J Infect Dev Ctries. 2012]bla(IMP) and bla(VIM) mediated carbapenem resistance in Pseudomonas and Acinetobacter species in India.Amudhan MS, Sekar U, Kamalanathan A, Balaraman S. J Infect Dev Ctries. 2012 Nov 26; 6(11):757-62. Epub 2012 Nov 26.
- Review [Metallo-beta-lactamase producing bacteria].[Nihon Rinsho. 2001]Review [Metallo-beta-lactamase producing bacteria].Iyobe S. Nihon Rinsho. 2001 Apr; 59(4):701-6.
- Table 2, Assays for the current probe discovery effort (ML302) - Probe Reports f...Table 2, Assays for the current probe discovery effort (ML302) - Probe Reports from the NIH Molecular Libraries Program
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