Figure 2Compound Preparation of Probe ML297
- PubChem BioAssay for Chemical ProbePubChem BioAssay records reporting screening data for the development of the chemical probe(s) described in this book chapter
- PubChem SubstanceRelated PubChem Substances
- Discovery and Characterization of VU0529331, a Synthetic Small-Molecule Activator of Homomeric G Protein-Gated, Inwardly Rectifying, Potassium (GIRK) Channels.[ACS Chem Neurosci. 2019]Discovery and Characterization of VU0529331, a Synthetic Small-Molecule Activator of Homomeric G Protein-Gated, Inwardly Rectifying, Potassium (GIRK) Channels.Kozek KA, Du Y, Sharma S, Prael FJ 3rd, Spitznagel BD, Kharade SV, Denton JS, Hopkins CR, Weaver CD. ACS Chem Neurosci. 2019 Jan 16; 10(1):358-370. Epub 2018 Sep 13.
- A novel small-molecule selective activator of homomeric GIRK4 channels.[J Biol Chem. 2022]A novel small-molecule selective activator of homomeric GIRK4 channels.Cui M, Xu K, Gada KD, Shalomov B, Ban M, Eptaminitaki GC, Kawano T, Plant LD, Dascal N, Logothetis DE. J Biol Chem. 2022 Jun; 298(6):102009. Epub 2022 May 4.
- GIRK1-mediated inwardly rectifying potassium current suppresses the epileptiform burst activities and the potential antiepileptic effect of ML297.[Biomed Pharmacother. 2018]GIRK1-mediated inwardly rectifying potassium current suppresses the epileptiform burst activities and the potential antiepileptic effect of ML297.Huang Y, Zhang Y, Kong S, Zang K, Jiang S, Wan L, Chen L, Wang G, Jiang M, Wang X, et al. Biomed Pharmacother. 2018 May; 101:362-370. Epub 2018 Mar 22.
- Review The Roles of Gβγ and Gα in Gating and Regulation of GIRK Channels.[Int Rev Neurobiol. 2015]Review The Roles of Gβγ and Gα in Gating and Regulation of GIRK Channels.Dascal N, Kahanovitch U. Int Rev Neurobiol. 2015; 123:27-85. Epub 2015 Jul 26.
- Review GIRK Channels as Candidate Targets for the Treatment of Substance Use Disorders.[Biomedicines. 2022]Review GIRK Channels as Candidate Targets for the Treatment of Substance Use Disorders.Kotajima-Murakami H, Ide S, Ikeda K. Biomedicines. 2022 Oct 13; 10(10). Epub 2022 Oct 13.
- Figure 2, Compound Preparation of Probe ML297 - Probe Reports from the NIH Molec...Figure 2, Compound Preparation of Probe ML297 - Probe Reports from the NIH Molecular Libraries Program
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