Figure 3. IC50 curve for probe ML226 (compound 12, SID 99445332) as determined by gel-based competitive-ABPP with FP-Rh (AID 504507) against target ABHD11 in a complex proteome lysate.

Figure 3IC50 curve for probe ML226 (compound 12, SID 99445332) as determined by gel-based competitive-ABPP with FP-Rh (AID 504507) against target ABHD11 in a complex proteome lysate

IC50 = 15 nM

From: Optimization and characterization of a triazole urea inhibitor for alpha/beta hydrolase domain-containing protein 11 (ABHD11): anti-probe for LYPLA1/LYPLA2 dual inhibitor ML211

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Probe Reports from the NIH Molecular Libraries Program [Internet].

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