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Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
Figure 3Activation of luciferase reporters driven by UPR sub-pathway promoters for the apoptotic (CHOP) and adaptive (XBP1) arms
Engineered CHO-K1 cell were incubated with ML291 for overnight (~16 hr) and luciferase induction measured with SteadyGlo™
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- Complementary cell-based high-throughput screens identify novel modulators of the unfolded protein response.[J Biomol Screen. 2011]Complementary cell-based high-throughput screens identify novel modulators of the unfolded protein response.Fribley AM, Cruz PG, Miller JR, Callaghan MU, Cai P, Narula N, Neubig RR, Showalter HD, Larsen SD, Kirchhoff PD, et al. J Biomol Screen. 2011 Sep; 16(8):825-35. Epub 2011 Aug 15.
- The balance between adaptive and apoptotic unfolded protein responses regulates β-cell death under ER stress conditions through XBP1, CHOP and JNK.[Mol Cell Endocrinol. 2015]The balance between adaptive and apoptotic unfolded protein responses regulates β-cell death under ER stress conditions through XBP1, CHOP and JNK.Chan JY, Luzuriaga J, Maxwell EL, West PK, Bensellam M, Laybutt DR. Mol Cell Endocrinol. 2015 Sep 15; 413:189-201. Epub 2015 Jun 30.
- Imaging of single cell responses to ER stress indicates that the relative dynamics of IRE1/XBP1 and PERK/ATF4 signalling rather than a switch between signalling branches determine cell survival.[Cell Death Differ. 2015]Imaging of single cell responses to ER stress indicates that the relative dynamics of IRE1/XBP1 and PERK/ATF4 signalling rather than a switch between signalling branches determine cell survival.Walter F, Schmid J, Düssmann H, Concannon CG, Prehn JH. Cell Death Differ. 2015 Sep; 22(9):1502-16. Epub 2015 Jan 30.
- Review Cerebral ischemia and the unfolded protein response.[J Neurochem. 2004]Review Cerebral ischemia and the unfolded protein response.DeGracia DJ, Montie HL. J Neurochem. 2004 Oct; 91(1):1-8.
- Review [The role of the adaptive stress response in the pathogenesis of neurodegenerative diseases, cancer and diabetes mellitus type 2].[Pol Merkur Lekarski. 2015]Review [The role of the adaptive stress response in the pathogenesis of neurodegenerative diseases, cancer and diabetes mellitus type 2].Rozpędek W, Markiewicz Ł, Diehl JA, Pytel D, Majsterek I. Pol Merkur Lekarski. 2015 Dec; 39(234):393-7.
- Figure 3, Activation of luciferase reporters driven by UPR sub-pathway promoters...Figure 3, Activation of luciferase reporters driven by UPR sub-pathway promoters for the apoptotic (CHOP) and adaptive (XBP1) arms - Probe Reports from the NIH Molecular Libraries Program
- Homologene neighbors for GEO Profiles (Select 79267078) (0)GEO Profiles
- Profile neighbors for GEO Profiles (Select 79267078) (200)GEO Profiles
- Gene Links for GEO Profiles (Select 79260618) (1)Gene
- BEX1 brain expressed X-linked 1 [Homo sapiens]BEX1 brain expressed X-linked 1 [Homo sapiens]Gene ID:55859Gene
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