Figure 1.

Figure 1.

NBIA Types

PKAN = pantothenate kinase-associated neurodegeneration

PLAN = PLA2G6-associated neurodegeneration

MPAN = mitochondrial membrane protein-associated neurodegeneration

BPAN = beta-propeller protein-associated neurodegeneration

Minor forms include those associated with pathogenic variants in ATP13A2, FA2H, FTL, CP, and DCAF17. Frequencies are based on 850 families worldwide collected over 25 years in a repository of neurodegeneration with brain iron accumulation.

From: Neurodegeneration with Brain Iron Accumulation Disorders Overview

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