Figure 1. Map of the Leukocyte Receptor Complex.

Figure 1Map of the Leukocyte Receptor Complex

At least 40 members of the Ig superfamily map to 19q13 within the extended LRC. The adapter genes DAP12 (KARAP) and DAP10 (KAP10) map to the centromeric end of the complex on band 19q13.1. The Siglecs and CD66 loci are extensive and more complex than indicated in this map. The LRC incorporates the ILT and KIR genes, and genes encoding FcαR, the activating receptor gene NKp46, and the collagen-binding receptor GPV1. (Adapted from Ref. 58, with permission from Dr. John Trowsdale and Blackwell Publishing Ltd.)

From: The KIR Gene Cluster

Cover of The KIR Gene Cluster
The KIR Gene Cluster [Internet].
Carrington M, Norman P.

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