Figure 8. Ribbon diagrams of KIR molecules.

Figure 8Ribbon diagrams of KIR molecules

(A) The KIR2DL2-Cw3 interface shows charged complementarity. Basic and acidic residues are shown in dark blue and red, respectively. (Reproduced from Ref. 93, with permission from Dr. Peter Sun and Nature Publishing Group.) (B) Shown is the top view of the α1 and α2 domains of the HLA-Cw4 molecule bound to KIR2DL1. (Reproduced from Ref. 92, with permission from Dr. Eric Long and Nature Publishing Group.) (C) Activating and inhibitory receptors are shown with their respective signaling motifs (ITIMs and ITAMs) and signaling molecules with which they associate. (Reproduced from Ref. 142, with permission from Dr. David Margulies and Blackwell Publishing Ltd.)

From: The KIR Gene Cluster

Cover of The KIR Gene Cluster
The KIR Gene Cluster [Internet].
Carrington M, Norman P.
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