Figure 3: . Diagrammatic view of the principle of NF-κB activation.

Figure 3:

Diagrammatic view of the principle of NF-κB activation. NF-κB (green), normally resides in the cytoplasm, once activated by stimuli (IL-1α, TNF-α ,etc) it translocates to the nucleus.

From: Nuclear Factor Kappa B (NF-κB) Translocation Assay Development and Validation for High Content Screening

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Assay Guidance Manual [Internet].
Markossian S, Grossman A, Arkin M, et al., editors.
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