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Metagenome-assembled genome: SRR5091531_bin.144_CONCOCT_v1.1_MAG

Identifiers
BioSample: SAMEA14085808; SRA: ERS11688939
Organism
uncultured Clostridia bacterium
cellular organisms; Bacteria; Bacillati; Bacillota; Clostridia; environmental samples
Attributes
collection date2015-10-01
broad-scale environmental contextHost-associated
local-scale environmental contextHuman
environmental mediumDigestive system
geographic locationChina
investigation typemetagenome-assembled genome
isolation sourcehuman gut metagenome
project nameGut microbiome make contributions to human host, and intestinal dysbiosis is associated with rheumatoid arthritis. Here we firstly demonstrated that the human gut microbiome related to rheumatoid arthritis could be divided into subtyping groups under different human enterotypes, which indicate the associations between rheumatoid arthritis and gut microbiome were diverse. In rheumatoid arthritis-related microbiota, Prevotella could be an indicator of early rheumatoid arthritis patients but insufficient to differentiate RA patients from healthy controls, and Bacteroides coprocola enriched in group 3 and Bacteroides dorei enriched in group 4 were considered to be as indicators of serious rheumatoid arthritis patients. Our findings provide additional evidences supporting that rheumatoid arthritis is a heterogeneous disease. Thus, the study of association between disease and gut microbiome should be conducted under different human gut enterotypes.
sample nameSRR5091531_bin.144_CONCOCT_v1.1_MAG
ENA-CHECKLISTERC000047
ENA-FIRST-PUBLIC2023-01-03
ENA-LAST-UPDATE2023-01-03
External IdSAMEA14085808
INSDC center aliasEBI
INSDC center nameEuropean Bioinformatics Institute
INSDC first public2023-01-03T00:33:08Z
INSDC last update2023-01-03T00:33:08Z
INSDC statuspublic
Submitter IdSRR5091531_bin.144_CONCOCT_v1.1_MAG
assembly qualityMany fragments with little to no review of assembly other than reporting of standard assembly statistics
assembly softwarespadesv3.12.0
binning parametersDefault
binning softwareCONCOCT v1.1
broker nameEMG broker account, EMBL-EBI
completeness score98.23
completeness softwareCheckM
contamination score0.02
geographic location (latitude)30.3
geographic location (longitude)120.2
metagenomic sourcehuman gut metagenome
sample derived fromSAMN06111958
scientific_nameuncultured Clostridia bacterium
sequencing methodIllumina HiSeq 2000
taxonomic identity markermulti-marker approach
Description

This sample represents a Third Party Annotation (TPA) Metagenome-Assembled Genome (MAG) assembled from the metagenomic run SRR5091531 of study SRP094805.

BioProject
PRJEB51075 Large-scale analysis of novel cellular microbes from the human gut biome
Retrieve all samples from this project

Submission
EBI; 2023-01-04
Accession:
SAMEA14085808
ID:
32562434

BioProject Nucleotide

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