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LUGEMM14 5-42

Identifiers
BioSample: SAMEA115098473; SRA: ERS17733220
Organism
Mus musculus (house mouse)
cellular organisms; Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Attributes
ageD22
collection datenot collected
genotypewild type genotype
geographic locationnot collected
isolatenot applicable
tissuelung
sample nameE-MTAB-13704:LUGEMM14 5-42
ENA first public2024-01-29
ENA-CHECKLISTERC000011
INSDC center nameOncology Data Science Oncology R&D
INSDC statuspublic
Submitter IdE-MTAB-13704:LUGEMM14 5-42
broker nameArrayExpress
common namehouse mouse
individualA42
sampling sitetumour
scientific_nameMus musculus
tumours_numbers11
Description

Protocols: Samples were collected from GEMMs lung lesions and assessed by MRI quantification of combined lung tumour lesions per animal before & after treatment RNA was extracted using the RNeasy Mini Kit (Qiagen; #74104). RNA concentration was determined by Qubit Flex Fluorometer (Invitrogen), RNA purity was determined using a NanoDrop Eight (Thermo Scientific) and RNA integrity was measured using a 4200 Tapestation (Agilent) Libraries were prepared using NEBNext Ultra II Directional RNA Library Prep Kit for Illumina (New England BioLabs; E7760L) or NEBNext® Ultra™ II RNA Library Prep Kit (New England BioLabs; E7770L) as per manufactuer’s guidelines. Ribosomal RNA was removed using the NEBNext® Poly(A) mRNA Magnetic Isolation Module (New England BioLabs; E7490L) .

BioProject
PRJEB71814 RNAseq analysis of tumours from GEMMS animals to determine the effect of different aPDL1 combinations on lung tumours in situ
Retrieve all samples from this project

Submission
EBI; 2024-01-30
Accession:
SAMEA115098473
ID:
39667663

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