BioProject

A previously undescribed, slow-growing scotochromogenic mycobacterium was identified on the basis of biochemical and nucleic acid analysis as well as mycolate cell wall analysis. More...

A previously undescribed, slow-growing scotochromogenic mycobacterium was identified on the basis of biochemical and nucleic acid analysis as well as mycolate cell wall analysis. Three isolates were discovered from skin lesions of a severe cellular immunodeficiency patient, an immunocompetent patient and a patient treated with biologic. Genotypic analysis using 16S rRNA misidentified this isolate as M. simiae. However, multiple gene analysis using the internal transcribed spacer between the 16S and 23S rRNA genes, and the rpoB and hsp65 genes revealed the presence of a novel mycobacterium. The antimicrobial susceptibility of this isolate was completely different from that of M. simiae. On the basis of these findings, we propose naming this new species Mycobacterium shigaense sp. nov. Less...