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Genome Information for Homo sapiens
Whole exome sequencing identified frequent driver mutations in a series of paediatric glioblastomas
We used microarray-based profiling to investigate differences in gene expression according to mutational status of driver genes
Overall design: RNA from 27 primary tumor samples was subject to QC by Agilent BioAnalyser analysis and then hybridised to an Affymetrix U133 Plus2 gene expression array
Accession | PRJNA150243; GEO: GSE34824 |
Data Type | Transcriptome or Gene expression |
Scope | Multiisolate |
Organism | Homo sapiens[Taxonomy ID: 9606] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens |
Publications | Schwartzentruber J et al., "Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma.", Nature, 2012 Jan 29;482(7384):226-31 |
Submission | Registration date: 1-Mar-2012 Pediatric Neuro Oncology, German Cancer Research Center |
Relevance | Medical |
Project Data:
Resource Name | Number of Links |
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Publications |
PubMed | 1 |
Other datasets |
GEO DataSets | 2 |
GEO Data DetailsParameter | Value |
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Data volume, Spots | 1100979 |
Data volume, Processed Mbytes | 17 |
Data volume, Supplementary Mbytes | 128 |