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Links from GEO DataSets

Accession: PRJNA125485 ID: 125485

Mus musculus (house mouse)

Activation or maintenance of a leukemia stem cell self-renewal pathway in downstream myeloid cells

See Genome Information for Mus musculus
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69882 additional projects are related by organism.
Activation or maintenance of a leukemia stem cell self-renewal pathway in downstream myeloid cells is an important component of AML development We generated either MLL-AF9 mediated murine leukemias that originate from committed progenitor (GMP) cells or Hoxa9/Meis1a mediated murine leukemias that originate from hematopoietic stem cells (HSC). More...
AccessionPRJNA125485; GEO: GSE20377
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismMus musculus[Taxonomy ID: 10090]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
Publications
  • Dietrich PA et al., "GPR84 sustains aberrant β-catenin signaling in leukemic stem cells for maintenance of MLL leukemogenesis.", Blood, 2014 Nov 20;124(22):3284-94
  • Wang Y et al., "The Wnt/beta-catenin pathway is required for the development of leukemia stem cells in AML.", Science, 2010 Mar 26;327(5973):1650-3
SubmissionRegistration date: 15-Mar-2010
Armstrong Lab, Pediatric Oncology, Dana-Farber Cancer Institute
RelevanceModel Organism
Project Data:
Resource NameNumber
of Links
Publications
PubMed2
PMC1
Other datasets
GEO DataSets2
GEO Data Details
ParameterValue
Data volume, Spots340350
Data volume, Processed Mbytes8
Data volume, Supplementary Mbytes32

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