Bap1 loss leads to decreased expression of lineage... (ID 522475) - BioProject

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Accession: PRJNA522475 ID: 522475

Bap1 loss leads to decreased expression of lineage specific commitment genes, and increased expression of pluripotency genes [RNA-seq] (African clawed frog)

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This project is a component of the Loss of Bap1 in Xenopus laevis embryos

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1 additional project is a component of the Loss of Bap1 in Xenopus laevis embryos.

292 additional projects are related by organism.

We performed morpholino-mediated knockdown of Bap1 protein expression in Xenopus laevis developing embryos, and analyzed gene expression at stage 12. More...

Accession	PRJNA522475; GEO: GSE126597
Data Type	Transcriptome or Gene expression
Scope	Multiisolate
Organism	Xenopus laevis[Taxonomy ID: 8355] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus; Xenopus laevis
Publications	Kuznetsov JN et al., "BAP1 regulates epigenetic switch from pluripotency to differentiation in developmental lineages giving rise to BAP1-mutant cancers.", Sci Adv, 2019 Sep;5(9):eaax1738
Submission	Registration date: 14-Feb-2019 Harbour, Ophthalmology, University of Miami Miller School of Medicine
Relevance	Model Organism

Project Data:

Resource Name	Number of Links
Sequence data
SRA Experiments	9
Publications
PubMed	1
PMC	1
Other datasets
BioSample	9
GEO DataSets	1

GEO Data Details

Parameter	Value
Data volume, Supplementary Mbytes	1285

SRA Data Details

Parameter	Value
Data volume, Gbases	26
Data volume, Mbytes	10314

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Bap1 loss leads to decreased expression of lineage specific commitment genes, and increased expression of pluripotency genes [RNA-seq] (African clawed frog)

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