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Accession: PRJNA1127511 ID: 1127511

A combinatorially complete epistatic fitness landscape in an enzyme active site

Selection based study where E. coli tryptophan auxotrophs harboring heterologously expressed beta subunits of the tryptophan synthases of Thermotoga maritima (TmTrpB) were grown in exogenous indole. More...
AccessionPRJNA1127511
Data TypeRaw sequence reads
ScopeMultispecies
Grants
  • "Multimodal Approaches for Leveraging Domain Knowledge with State-of-the-Art Machine Learning to Engineer Biocatalysts" (Grant ID DE-SC0022218, U.S. Department of Energy, Office of Science, Office of Basic Energy Sciences)
SubmissionRegistration date: 24-Jun-2024
California Institute of Technology
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments89
Other datasets
BioSample89
SRA Data Details
ParameterValue
Data volume, Gbases188
Data volume, Mbytes57572

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