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Genome Information for Oryctolagus cuniculus
To investigate the effect of mechanical ventilation and mechanical ventilationon with PEEP application on diaphragmatic dysfunction, we established a model of mechanical ventilation on New Zealand rabbit, in which rabbits in the experimental group were ventilated with/without PEEP application for 48 hours continuously
Overall design: Comparative gene expression profiling analysis of RNA-seq data on diaphragm between the control group and the mechanical ventilation group
Accession | PRJNA951382; GEO: GSE228739 |
Data Type | Transcriptome or Gene expression |
Scope | Multiisolate |
Organism | Oryctolagus cuniculus[Taxonomy ID: 9986] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus; Oryctolagus cuniculus |
Publications | Shen W et al., "Cellular senescence contributes to mechanical ventilation-induced diaphragm dysfunction by upregulating p53 signalling pathways.", BMC Pulm Med, 2023 Dec 14;23(1):509 |
Submission | Registration date: 2-Apr-2023 School of Pharmaceutical Sciences, Jilin University |
Relevance | Model Organism |
Project Data:
Resource Name | Number of Links |
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Sequence data |
SRA Experiments | 9 |
Publications |
PubMed | 1 |
PMC | 1 |
Other datasets |
BioSample | 9 |
GEO DataSets | 1 |