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Accession: PRJNA719832 ID: 719832

Enhanced efficacy of aurora kinase inhibitors in G2/M checkpoint deficient TP53 mutant uterine carcinomas is linked to the summation of LKB1-AKT-p53 interactions

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series
AccessionPRJNA719832; GEO: GSE171516
TypeUmbrella project
PublicationsLynch KN et al., "Enhanced Efficacy of Aurora Kinase Inhibitors in G2/M Checkpoint Deficient TP53 Mutant Uterine Carcinomas Is Linked to the Summation of LKB1-AKT-p53 Interactions.", Cancers (Basel), 2021 May 3;13(9)
SubmissionRegistration date: 5-Apr-2021
Medical Oncology, Dana-Farber Cancer Institute
RelevanceSuperseries
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments24
Publications
PubMed1
PMC1
Other datasets
BioSample24
GEO DataSets4
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes11
SRA Data Details
ParameterValue
Data volume, Gbases170
Data volume, Mbytes55603
Enhanced efficacy of aurora kinase inhibitors in G2/M checkpoint deficient TP53 mutant uterine carcinomas is linked to the summation of LKB1-AKT-p53 interactions encompasses the following 3 sub-projects:
Project TypeNumber of Projects
Other2
BioProject
accession
OrganismTitle
PRJNA719835Homo sapiensEnhanced efficacy of aurora kinase inhibitors in G2/M checkpoint deficient TP53 mutant uterine carcinomas is linked to the summation of LKB1-AKT-p53 interactions [exome-seq] (Medical Oncology, Dana-Farber...)
PRJNA719836Homo sapiensEnhanced efficacy of aurora kinase inhibitors in G2/M checkpoint deficient TP53 mutant uterine carcinomas is linked to the summation of LKB1-AKT-p53 interactions [WGS] (Medical Oncology, Dana-Farber...)
Transcriptome or Gene expression1
BioProject
accession
OrganismTitle
PRJNA719834Homo sapiensEnhanced efficacy of aurora kinase inhibitors in G2/M checkpoint deficient TP53 mutant uterine carcinomas is linked to the summation of LKB1-AKT-p53 interactions [RNA-seq] (Medical Oncology, Dana-Farber...)

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