In this project, the Baylor College of Medicine Human
Genome Sequencing Center is performing whole genome sequencing and analysis
of common marmosets (Callithrix jacchus). More...
In this project, the Baylor College of Medicine Human
Genome Sequencing Center is performing whole genome sequencing and analysis
of common marmosets (Callithrix jacchus). Marmosets are used for a variety of
biomedical research studies, including but not limited to neuroscience,
cognition and behavior, reproductive biology, parental behavior and infant
development, endocrinology and other fields. The Baylor genome center is
generating 30x whole genome sequence coverage using Illumina Nova-Seq
sequencing methods, and using standard software tools to map reads, identify
single nucleotide variants and annotate variants where possible. DNA samples
for sequencing are currently provided by Dr. Jon Levine (Wisconsin National
Primate Research Center), Dr. Corrine Ross (Southwest National Primate
Research Center). We intend to include other marmoset colonies as samples
become available. These data will be used to assist in the genetic management
of marmoset breeding colonies, identify potentially functional genetic
variants, attempt to identify new spontaneous genetic mutations that lead to
new models of genetic disease and evaluate genetic differences among captive
research colonies of marmosets, as well as differences between captive and
wild marmoset populations. Less...