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Accession: PRJNA952614 ID: 952614

Whole genome bisulfite-seq analysis of control and Dnmt3a conditional knockout (cKO) retinal ganglion cells at 2 days post optic nerve crush (house mouse)

See Genome Information for Mus musculus
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71485 additional projects are related by organism.
Dnmt3a deficiency in retinal ganglion cells promotes axon regeneration in an optic nerve crush mouse model. More...
AccessionPRJNA952614; GEO: GSE229034
Data TypeEpigenomics
ScopeMultiisolate
OrganismMus musculus[Taxonomy ID: 10090]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
PublicationsTai WL et al., "Suppressing DNMT3a Alleviates the Intrinsic Epigenetic Barrier for Optic Nerve Regeneration and Restores Vision in Adult Mice.", bioRxiv, 2023 Nov 23;
Grants
  • "Innate and Adaptive Immunity in the Pathogenesis of Glaucoma" (Grant ID R01 EY031696, National Eye Institute)
  • "Histone and DNA methyltransferases in optic nerve regeneration" (Grant ID R21 EY033882, National Eye Institute)
  • "Retinal Ganglion Cell Replacement in Clinically Relevant Models of Optic Neuropathy" (Grant ID U24 EY029893, National Eye Institute)
SubmissionRegistration date: 5-Apr-2023
Schepens Eye Research Institute
RelevanceModel Organism
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments2
Publications
PubMed1
PMC1
Other datasets
BioSample2
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes1310
SRA Data Details
ParameterValue
Data volume, Gbases236
Data volume, Mbytes82398

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