Divergent outcomes of anti-PD-L1 treatment coupled... (ID 885044) - BioProject

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Accession: PRJNA885044 ID: 885044

Divergent outcomes of anti-PD-L1 treatment coupled with host-intrinsic differences in TCR repertoire and distinct T cell activation states in responding versus non-responding tumors (house mouse)

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Differential responses to immune checkpoint inhibitors (ICI) may be attributed to tumor-intrinsic factors or environmental cues; however, these mechanisms cannot fully explain the variable ICI responses in different individuals. More...

Accession	PRJNA885044; GEO: GSE214348
Scope	Multiisolate
Organism	Mus musculus[Taxonomy ID: 10090] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
Publications	John J et al., "Divergent outcomes of anti-PD-L1 treatment coupled with host-intrinsic differences in TCR repertoire and distinct T cell activation states in responding versus non-responding tumors.", Front Immunol, 2022;13:992630
Submission	Registration date: 28-Sep-2022 Jing Hong Wang Lab, Department of Medicine, University of Pittsburgh
Relevance	Model Organism

Project Data:

Resource Name	Number of Links
Sequence data
SRA Experiments	32
Publications
PubMed	1
PMC	1
Other datasets
BioSample	32
GEO DataSets	1

GEO Data Details

Parameter	Value
Data volume, Supplementary Mbytes	4841

SRA Data Details

Parameter	Value
Data volume, Gbases	1,379
Data volume, Tbytes	0.46

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Divergent outcomes of anti-PD-L1 treatment coupled with host-intrinsic differences in TCR repertoire and distinct T cell activation states in responding versus non-responding tumors (house mouse)

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