Global DNA methylation analysis of cancer-associat... (ID 879056) - BioProject

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Accession: PRJNA879056 ID: 879056

Global DNA methylation analysis of cancer-associated fibroblasts reveals extensive epigenetic rewiring linked with RUNX1 upregulation in breast cancer stroma [ly6c] (house mouse)

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This project is a component of the Global DNA methylation analysis of cancer-associated fibroblasts reveals extensive epigenetic rewiring linked with RUNX1 upregulation in breast cancer stroma

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3 additional projects are components of the Global DNA methylation analysis of cancer-associated fibroblasts reveals extensive epigenetic rewiring linked with RUNX1 upregulation in breast cancer stroma.

71031 additional projects are related by organism.

We performed RNA seq to charachterize the transcriptome of specific cancer associates fibroblasts (pCAFs) sub-populations (Ly6c+ vs Ly6c- pCAFs) Overall design: 4T1 cells were injected orthotopcally into the mammary fat pad of balb\c mice, tumors were harvested and digested after reaching a size of 1 cm. More...

Accession	PRJNA879056; GEO: GSE213074
Data Type	Transcriptome or Gene expression
Scope	Multiisolate
Organism	Mus musculus[Taxonomy ID: 10090] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
Publications	Halperin C et al., "Global DNA Methylation Analysis of Cancer-Associated Fibroblasts Reveals Extensive Epigenetic Rewiring Linked with RUNX1 Upregulation in Breast Cancer Stroma.", Cancer Res, 2022 Nov 15;82(22):4139-4152
Submission	Registration date: 10-Sep-2022 Scherz-Shouval, Weizmann institute of sciences
Relevance	Model Organism

Project Data:

Resource Name	Number of Links
Sequence data
SRA Experiments	6
Publications
PubMed	1
Other datasets
BioSample	6
GEO DataSets	1

GEO Data Details

Parameter	Value
Data volume, Supplementary Mbytes	1

SRA Data Details

Parameter	Value
Data volume, Gbases	2
Data volume, Mbytes	1004

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Global DNA methylation analysis of cancer-associated fibroblasts reveals extensive epigenetic rewiring linked with RUNX1 upregulation in breast cancer stroma [ly6c] (house mouse)

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