This SuperSeries is composed of the SubSeries listed below.
Overall design: Refer to individual Series
| Accession | PRJNA875396; GEO: GSE212417 |
| Type | Umbrella project |
| Grants | - "Computational analysis of single-nucleus sequencing data for studying the cell type-specific basis of opioid use disorders" (Grant ID F31 DA056226, National Institute on Drug Abuse)
- "Center for Genetic Studies of Drug Abuse in Outbred Rats" (Grant ID P50 DA037844, National Institute on Drug Abuse)
- "Identification of Genetic Variants that Contribute to Compulsive Cocaine Intake inRats" (Grant ID U01 DA043799, National Institute on Drug Abuse)
- "Identification of Genetic Variants that Contribute to Compulsive Cocaine Intake inRats" (Grant ID U01 DA043799, National Institute on Drug Abuse)
- "Single-cell resolution analysis of chromatin accessibility and gene expression changes in a model of drug addiction" (Grant ID U01 DA050239, National Institute on Drug Abuse)
|
| Submission | Registration date: 31-Aug-2022
University of California San Diego |
| Relevance | Superseries |
Project Data:
| Resource Name | Number
of Links |
|---|
| Sequence data |
| SRA Experiments | 35 |
| Other datasets |
| BioSample | 35 |
| GEO DataSets | 5 |
Cocaine addiction-like behaviors are associated with long-term changes in gene regulation, energy metabolism, and GABAergic inhibition within the amygdala encompasses the following 4 sub-projects:
| Project Type | Number of Projects |
| Epigenomics | 2 |
BioProject
accession | Organism | Title |
|---|
| PRJNA875404 | Rattus norvegicus | A single-cell atlas of gene expression and chromatin accessibility changes associated with cocaine addiction in the rat amygdala [snATAC-seq] (University of California...) | | PRJNA985691 | Rattus norvegicus | A single-cell atlas of gene expression and chromatin accessibility changes associated with cocaine addiction in the rat amygdala (snATAC-Seq Multiome) (University of California...) |
|
| Transcriptome or Gene expression | 2 |
BioProject
accession | Organism | Title |
|---|
| PRJNA875405 | Rattus norvegicus | A single-cell atlas of gene expression and chromatin accessibility changes associated with cocaine addiction in the rat amygdala [snRNA-seq] (University of California...) | | PRJNA985687 | Rattus norvegicus | A single-cell atlas of gene expression and chromatin accessibility changes associated with cocaine addiction in the rat amygdala (snRNA-Seq Multiome) (University of California...) |
|