Dyrk1a dosage effects on the transcriptome of embr... (ID 804913) - BioProject

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Accession: PRJNA804913 ID: 804913

Dyrk1a dosage effects on the transcriptome of embryonic hearts from the Dp1Tyb mouse model of Down syndrome using bulk RNAseq (house mouse)

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This project is a component of the Down Syndrome

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4 additional projects are components of the Down Syndrome.

We performed bulk RNAseq on whole hearts from E13.5 Dp1Tyb embryos and from wild-type littermates, as well as hearts from E13. More...

Accession	PRJNA804913; GEO: GSE196445
Data Type	Transcriptome or Gene expression
Scope	Multiisolate
Organism	Mus musculus[Taxonomy ID: 10090] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
Publications	Lana-Elola E et al., "Increased dosage of DYRK1A leads to congenital heart defects in a mouse model of Down syndrome.", Sci Transl Med, 2024 Jan 24;16(731):eadd6883
Submission	Registration date: 9-Feb-2022 Francis Crick Institute
Relevance	Model Organism

Project Data:

Parameter	Value
Data volume, Supplementary Mbytes	5

Parameter	Value
Data volume, Gbases	38
Data volume, Mbytes	12709