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Accession: PRJNA719840 ID: 719840

HCMV transcriptome during early lytic infection

Purpose: to investigate expression of HCMV and cellular RNAs at early times post-infection in a lytic model Overall design: MRC5 cells were infected with the TB40/E wtGFP strain of HCMV. Cells were cultured for 24 hours, and then processed for RNAseq analysis.
AccessionPRJNA719840; GEO: GSE171520
Data TypeTranscriptome or Gene expression
ScopeMultispecies
PublicationsForte E et al., "Critical Role for the Human Cytomegalovirus Major Immediate Early Proteins in Recruitment of RNA Polymerase II and H3K27Ac To an Enhancer-Like Element in OriLyt.", Microbiol Spectr, 2023 Feb 14;11(1):e0314422
Grants
  • "Integrating Mechanistic Insights from Diverse Models to Prevent CMV Reactivation following Transplantation" (Grant ID P01 AI112522, National Institute of Allergy and Infectious Diseases Extramural Activities)
SubmissionRegistration date: 5-Apr-2021
Northwestern University
RelevanceUnknown
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments2
Publications
PubMed1
PMC1
Other datasets
BioSample2
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes142
SRA Data Details
ParameterValue
Data volume, Gbases24
Data volume, Mbytes7305

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