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Accession: PRJNA690708 ID: 690708

Linker histone H1.8 inhibits chromatin-binding of condensins and DNA topoisomerase II to tune chromosome compaction and individualization (African clawed frog)

See Genome Information for Xenopus laevis
Hi-C on reconstituted mitotic chromosomes in Xenopus system in IGG or specific depleted egg extracts to study to role of condensin and linker histone in chromosome condensation Overall design: Hi-C on reconstituted mitotic chromosomes in Xenopus system
AccessionPRJNA690708; GEO: GSE164434
ScopeMultiisolate
OrganismXenopus laevis[Taxonomy ID: 8355]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus; Xenopus laevis
PublicationsChoppakatla P et al., "Linker histone H1.8 inhibits chromatin binding of condensins and DNA topoisomerase II to tune chromosome length and individualization.", Elife, 2021 Aug 18;10
SubmissionRegistration date: 8-Jan-2021
Dekker lab, Systems Biology, University of Massachusetts Medical School
RelevanceModel Organism
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments25
Publications
PubMed1
PMC1
Other datasets
BioSample25
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes7586
SRA Data Details
ParameterValue
Data volume, Gbases215
Data volume, Mbytes80355

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